32223-64-6

Upstream product

• 75-44-5 phosgene 
• 4469-80-1 4-propoxyaniline 
• 5438-19-7 4-propoxybenzoic acid 

Downstream Products

• 112922-91-5 (4-Propoxy-phenyl)-carbamic acid 2-morpholin-4-yl-ethyl ester; hydrochloride 
• 581070-48-6 4-fluorobenzaldehyde O-[[(4-propoxy-phenyl)amino]carbonyl]oxime 
• 18687-82-6 propan-2-one O-[[(4-propoxy-phenyl)amino]carbonyl]oxime 
• 581070-45-3 benzaldehyde O-[[(4-propoxy-phenyl)amino]carbonyl]oxime 
• 126381-31-5 3-(1-Naphthylmethyl)-4-(p-n-propoxyphenyl)-1,2,4-triazolin-5-on 
• 126381-22-4 5-(4-Methyl-benzyl)-4-(4-propoxy-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one 
• 126381-16-6 3-Benzyl-4-(p-n-propoxyphenyl)-1,2,4-triazolin-5-on 

Relevant academic research and scientific papers

Oxime Carbamate-Discovery of a series of novel FAAH inhibitors

A series of novel oxime carbamates have been identified as potent inhibitors of the key regulatory enzyme of the endocannabinoid signaling system, fatty acid amide hydrolase (FAAH). In this Letter, the rationale behind the discovery and the biological evaluations of this novel class of FAAH inhibitors are presented. Both in vitro and in vivo results of selected targets are discussed, along with inhibition kinetics and molecular modeling studies.1.

Positive allosteric modulators of the nicotinic acetylcholine receptor

The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which α7 nAChR is known to be involved.

Synthesis of isocyanates from nitroalkanes

A process for the preparation of aromatic isocyanates from nitroalkanes. A nitromethyl aromatic compound of the general formula: STR1 wherein R and R1 represent hydrogen, halogen, a C1 -C5 alkyl radical, a C1 -C4 alkoxy radical, nitro, isocyanato, an alkoxycarbonylamino, or nitromethyl radical, with R and R1 being the same or different, is heated in the presence of an effective amount of a Lewis acid or Bronsted acid substance to effect a dehydrogenation-isomerization reaction to yield an aromatic isocyanate of the general formula: STR2 The product of the reaction may be recovered as the aromatic isocyanate or the alcohol adduct, a carbamate.