322429-05-0

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 322428-68-2 (1E)-5-(methoxymethyloxy)-1-pentenyl iodide 
• 322428-72-8 (2R,3Z,6E)-10-(methoxymethyloxy)-2,4-dimethyl-3,6-decadien-1-ol 
• 322428-74-0 (1E,3R,4Z,7E)-11-(methoxymethyloxy)-3,5-dimethyl-1,4,7-undecatrienyl iodide 
• 179241-87-3 methyl (3E,6Z,8S,9E)-2-(6,8-dimethyl-3,6,9-undecatrienyl)-oxazole-4-carboxylate 
• 322428-96-6 (R)-2-Methoxy-3-[(2R,4R,6R)-6-methoxy-4-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-propionaldehyde 
• 322428-35-3 (2Z,4R)-5-(tert-butyldiphenylsiloxy)-2,4-dimethyl-2-pentenyl bromide 
• 322428-66-0 (Z,R)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpent-2-en-1-ol 
• 322428-82-0 methyl [2S,2(4E,7Z,9S,10E)]-2-[7,9-dimethyl-4,7,10-dodecatrienyl-1-carbonyl(amino)]-3-hydroxypropanoate 
• 322428-64-8 methyl (2Z,4R)-5-(tert-butyldiphenylsiloxy)-2,4-dimethyl-2-pentenoate 
• 322428-53-5 (1E,3R)-4-[(2R,4R,6R)-4-p-methoxybenzyloxy-2-methoxy-2-methyltetrahydropyran-6-yl]-1-phenyl-3-methoxy-1-butene 
• 322428-47-7 (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene 
• 322428-51-3 (1E,3R)-4-[(2R,4R,6R)-4-p-methoxybenzyloxy-2-methoxy-2-methyltetrahydropyran-6-yl]-1-phenyl-3-hydroxy-1-butene 
• 322428-33-1 (4R)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentanone 

Downstream Products

• 322428-87-5 2'-((S,3E,6Z,9E)-6,8-dimethylundeca-3,6,9-trien-1-yl)-4-((R)-1-methoxy-2-((2R,4R,6R)-6-methoxy-4-((4-methoxybenzyl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)ethyl)-2,4'-bioxazole 
• 322428-85-3 (3R)-4-[(2R,4R,6R)-4-p-methoxybenzyloxy-2-methoxy-2-methyltetrahydropyran-6-yl]-2-[(3E,6Z,8S,9E)-2-(6,8-dimethyl-3,6,9-undecatrienyl)oxazole-4-carbonylamino]-3-methoxy-1-butanol 

Relevant academic research and scientific papers

Total synthesis of (-)-hennoxazole A

The antiviral marine natural product (-)-hennoxazole A was efficiently synthesized by a convergent approach. The stereoselective synthesis of the functionalized tetrahydropyran fragment was accomplished by the Mukaiyama aldol reaction, chelation-controlle

Total synthesis of the antiviral marine natural product (-)-hennoxazole A.

[structure:see text] The marine natural product hennoxazole A was synthesized by a convergent approach. The diastereoselective Mukaiyama aldol reaction with beta-alkoxy aldehyde was used to construct the tetrahydropyran segment, and the preparation of the