322428-35-3

Upstream product

• 92817-88-4 (2S)-3-{[tert-butyl(diphenyl)silyl]oxy}-2-methylpropanal 
• 322428-64-8 methyl (2Z,4R)-5-(tert-butyldiphenylsiloxy)-2,4-dimethyl-2-pentenoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 
• 322428-66-0 (Z,R)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpent-2-en-1-ol 

Downstream Products

• 322428-87-5 2'-((S,3E,6Z,9E)-6,8-dimethylundeca-3,6,9-trien-1-yl)-4-((R)-1-methoxy-2-((2R,4R,6R)-6-methoxy-4-((4-methoxybenzyl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)ethyl)-2,4'-bioxazole 
• 322428-85-3 (3R)-4-[(2R,4R,6R)-4-p-methoxybenzyloxy-2-methoxy-2-methyltetrahydropyran-6-yl]-2-[(3E,6Z,8S,9E)-2-(6,8-dimethyl-3,6,9-undecatrienyl)oxazole-4-carbonylamino]-3-methoxy-1-butanol 
• 322429-05-0 2-((3E,6Z,9E)-(S)-6,8-Dimethyl-undeca-3,6,9-trienyl)-oxazole-4-carboxylic acid {(R)-1-(tert-butyl-diphenyl-silanyloxymethyl)-2-methoxy-3-[(2R,4R,6R)-6-methoxy-4-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-propyl}-amide 
• 322428-70-6 (2R,3Z,6E)-1-(tert-butyldiphenylsiloxy)-10-(methoxymethyloxy)-2,4-dimethyl-3,6-decadiene 

Relevant academic research and scientific papers

Total synthesis of (-)-hennoxazole A

The antiviral marine natural product (-)-hennoxazole A was efficiently synthesized by a convergent approach. The stereoselective synthesis of the functionalized tetrahydropyran fragment was accomplished by the Mukaiyama aldol reaction, chelation-controlle

Total synthesis of the antiviral marine natural product (-)-hennoxazole A.

[structure:see text] The marine natural product hennoxazole A was synthesized by a convergent approach. The diastereoselective Mukaiyama aldol reaction with beta-alkoxy aldehyde was used to construct the tetrahydropyran segment, and the preparation of the