3225-74-9

Basic information

• Product Name: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL
• Synonyms: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL;2-hydroxy-2-(2-fluorophenyl)-ethanamine
• CAS NO: 3225-74-9
• Molecular Formula: C₈H₁₀FNO
• Molecular Weight: 155.17
• Mol File: 3225-74-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 287.4oCat760mmHg
• Flash Point: 127.6oC
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL(3225-74-9)
• EPA Substance Registry System: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL(3225-74-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 3225-74-9(Hazardous Substances Data)

Usage

Uses

2-Amino-1-(2-fluorophenyl)ethanol is used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

InChI:InChI=1/C8H10FNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4,8,11H,5,10H2

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 446-52-6 2-Fluorobenzaldehyde 
• 82128-76-5 α-[(trimethylsilyl)oxy]-α-(o-fluorophenyl)acetonitrile 

Downstream Products

• 1426152-49-9 C₁₅H₁₃FN₄O₂S 

Relevant articles and documents

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

A series of 1-aryl-2-(((6-aryl)pyrimidin-4-yl)amino)ethanols have been found to be competitive inhibitors of fatty acid amide hydrolase (FAAH). One member of this class, JNJ-40413269, was found to have excellent pharmacokinetic properties, demonstrated robust central target engagement, and was efficacious in a rat model of neuropathic pain.

Heteroarylethanol-pyridylalkylamines for controlling animal growth

A compound for promoting livestock production and for controlling obesity in humans and animals, of the formula STR1 in which A represents =CH-- or =N--, R0 represents hydrogen or methyl, R1 and R3 each independently represents hydrogen, hydroxyl, halogen, cyano, alkyl, halogenoalkyl, hydroxyalkyl, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, halogenoalkoxy, halogenoalkylthio, NHSO2 -alkyl, R2 represents hydrogen, hydroxyl, alkoxy or the radical --NR5 R6, R4 represents hydrogen, C1 -C10 -alkyl which is optionally substituted by hydroxyl, halogen, alkoxy, acyloxy or the radical --NH7 R8, or represents the radical COR9 or the radical --O--Z--R10, Z represents C1 -C10 -alkylene, -alkenylene or alkynylene, R5 represents hydrogen or alkyl, R6 represents hydrogen, alkyl, halogenoalkyl or acyl, or R5 and R6 together with the adjoining N atom form a saturated or unsaturated heterocyclic 4-, 5- or 6-membered ring, R7 and R8 each independently represents hydrogen, optionally substituted alkyl, optionally substituted aryl, R9 represents hydroxyl, alkoxy or the radical --NR7 R8, R10 represents hydroxyl, alkoxy, acyloxy, optionally substituted aryloxy or aralkyloxy, with the substituent R4 and the alkylamino group in the pyridyl ring of the formula I being in the p position with respect to one another, or a physiologically tolerated salt thereof, or, if A represents nitrogen, optionally the N-oxide thereof.