3225-74-9

Usage

Uses

Used in Organic Synthesis:
2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL is used as a building block for the synthesis of more complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the creation of novel compounds with specific properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL is used as an intermediate in the development of new drugs. Its structural diversity and reactivity enable the design of potential therapeutic agents targeting various diseases and conditions.
Used in Agrochemicals:
2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL is also utilized in the agrochemical sector for the synthesis of active ingredients in pesticides and other agricultural chemicals. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved crop protection and management.
Used in Dyestuff Industry:
In the dyestuff industry, 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL serves as a key component in the production of various dyes and pigments. Its unique chemical properties contribute to the development of dyes with specific color characteristics and improved performance in different applications, such as textiles, plastics, and printing inks.

InChI:InChI=1/C8H10FNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4,8,11H,5,10H2

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 446-52-6 2-Fluorobenzaldehyde 
• 82128-76-5 α-[(trimethylsilyl)oxy]-α-(o-fluorophenyl)acetonitrile 

Downstream Products

• 1426152-49-9 C₁₅H₁₃FN₄O₂S 

Relevant academic research and scientific papers

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

A series of 1-aryl-2-(((6-aryl)pyrimidin-4-yl)amino)ethanols have been found to be competitive inhibitors of fatty acid amide hydrolase (FAAH). One member of this class, JNJ-40413269, was found to have excellent pharmacokinetic properties, demonstrated robust central target engagement, and was efficacious in a rat model of neuropathic pain.

PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS

A compound of formula (I) or a salt or solvate thereof: Formula (1) compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such mono-anilino pyrimidine derivative

Heteroarylethanol-pyridylalkylamines for controlling animal growth

A compound for promoting livestock production and for controlling obesity in humans and animals, of the formula STR1 in which A represents =CH-- or =N--, R0 represents hydrogen or methyl, R1 and R3 each independently represents hydrogen, hydroxyl, halogen, cyano, alkyl, halogenoalkyl, hydroxyalkyl, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, halogenoalkoxy, halogenoalkylthio, NHSO2 -alkyl, R2 represents hydrogen, hydroxyl, alkoxy or the radical --NR5 R6, R4 represents hydrogen, C1 -C10 -alkyl which is optionally substituted by hydroxyl, halogen, alkoxy, acyloxy or the radical --NH7 R8, or represents the radical COR9 or the radical --O--Z--R10, Z represents C1 -C10 -alkylene, -alkenylene or alkynylene, R5 represents hydrogen or alkyl, R6 represents hydrogen, alkyl, halogenoalkyl or acyl, or R5 and R6 together with the adjoining N atom form a saturated or unsaturated heterocyclic 4-, 5- or 6-membered ring, R7 and R8 each independently represents hydrogen, optionally substituted alkyl, optionally substituted aryl, R9 represents hydroxyl, alkoxy or the radical --NR7 R8, R10 represents hydroxyl, alkoxy, acyloxy, optionally substituted aryloxy or aralkyloxy, with the substituent R4 and the alkylamino group in the pyridyl ring of the formula I being in the p position with respect to one another, or a physiologically tolerated salt thereof, or, if A represents nitrogen, optionally the N-oxide thereof.

Secondary amines, their preparation and use in pharmaceutical compositions

Compounds having the formula: STR1 where R1, R2, R3, R4, R5, Y and X are as defined hereinbelow, are useful for the reduction of abnormally high blood glucose and lipid levels in the treatment of obesity or hyperglycaemia.