82128-76-5Relevant academic research and scientific papers
Crystal transformation in Mn(ii) metal-organic frameworks based on a one-dimensional chain precursor
Fan, Yong,Gong, Yiran,Jiang, Yansong,Liu, Rui,Wang, Li,Xu, Jianing
, p. 9540 - 9546 (2021/07/17)
The solvothermal reaction of Mn(ii) salts and 5-((4′-(tetrazol-5′′-yl)benzyl)oxy)isophthalic acid (H3L) affords an Mn(ii) based coordination polymer Mn(H2L)2(H2O)2(1), which possesses a one-dimensiona
Temperature-induced Sn(II) supramolecular isomeric frameworks as promising heterogeneous catalysts for cyanosilylation of aldehydes
Sheng, Kai,Fan, Li-Ming,Tian, Xue-Fei,Gupta, Rakesh Kumar,Gao, Linna,Tung, Chen-Ho,Sun, Di
, p. 182 - 186 (2019/12/24)
Two novel Sn(II) supramolecular isomeric frameworks, with the identical formula of {(NH2Me2)2[Sn(BDC)(SO4)]}n, Sn-CP-1-α (1) and Sn-CP-1-β (2) (H2BDC=terephthalic acid) were synthesized und
Manganese-organic framework assembled by 5-((4′-(tetrazol-5″-yl)benzyl)oxy)isophthalic acid: A solvent-free catalyst for the formation of carbon–carbon bond
Jiang, Yansong,Xu, Jianing,Zhu, Ziqian,Jiang, Changwei,Ma, Lin,Wang, Hui,Wang, Li,Fan, Yong
supporting information, (2020/05/25)
A new three-dimensional manganese-based metal–organic framework Mn4L2(HL)(H2O)5, (1), based on semi-rigid 5-((4′-(tetrazol-5′’-yl)benzyl)oxy)isophthalic acid ligand (H3L) have been prepared and charac
Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain
Kramer, Jan S.,Woltersdorf, Stefano,Duflot, Thomas,Hiesinger, Kerstin,Lillich, Felix F.,Kn?ll, Felix,Wittmann, Sandra K.,Klingler, Franca-M.,Brunst, Steffen,Chaikuad, Apirat,Morisseau, Christophe,Hammock, Bruce D.,Buccellati, Carola,Sala, Angelo,Rovati, G. Enrico,Leuillier, Matthieu,Fraineau, Sylvain,Rondeaux, Julie,Hernandez-Olmos, Victor,Heering, Jan,Merk, Daniel,Pogoryelov, Denys,Steinhilber, Dieter,Knapp, Stefan,Bellien, Jeremy,Proschak, Ewgenij
, p. 8443 - 8460 (2019/10/16)
The emerging pharmacological target soluble epoxide hydrolase (sEH) is a bifunctional enzyme exhibiting two different catalytic activities that are located in two distinct domains. Although the physiological role of the C-terminal hydrolase domain is well-investigated, little is known about its phosphatase activity, located in the N-terminal phosphatase domain of sEH (sEH-P). Herein we report the discovery and optimization of the first inhibitor of human and rat sEH-P that is applicable in vivo. X-ray structure analysis of the sEH phosphatase domain complexed with an inhibitor provides insights in the molecular basis of small-molecule sEH-P inhibition and helps to rationalize the structure-activity relationships. 4-(4-(3,4-Dichlorophenyl)-5-phenyloxazol-2-yl)butanoic acid (22b, SWE101) has an excellent pharmacokinetic and pharmacodynamic profile in rats and enables the investigation of the physiological and pathophysiological role of sEH-P in vivo.
Synthesis of organoaluminum chalcogenides and their applications in Lewis acid catalysis
Ding, Yi,Ma, Xiaoli,Liu, Yashuai,Liu, Wenqing,Ni, Congjian,Yan, Ben,Yan, Li,Yang, Zhi
, (2019/08/27)
Two chalcogenide bridged bi-aluminum compounds [LAl(NMe3)(μ-S)Al(NMe3)L] (1) and [LAl(NMe3)(μ-Se)Al(NMe3)L] (2) were synthesized by reacting LAlH(NMe3) (L = 4-methylbenzylidene-o-aminothiophenol) with
PhI(OAc)2-mediated alkoxyoxygenation of β,γ-unsaturated ketoximes: Preparation of isoxazolines bearing two contiguous tetrasubstituted carbons
Ye, Chenghao,Kou, Xuezhen,Yang, Guoqiang,Shen, Jiefeng,Zhang, Wanbin
supporting information, p. 1148 - 1152 (2019/03/26)
A PhI(OAc)2-promoted dioxygenation of allyl oximes, including one alkoxylation, has been developed. This reaction can give isoxazoline products bearing two contiguous tetrasubstituted carbons. Various oximes substrates bearing different aryl groups and tetrasubstituted-olefin moieties were compatible with the mild reaction conditions. A two-electron oxidation pathway was proposed based on results of preliminary mechanistic studies.
Low-valent magnesium(i)-catalyzed cyanosilylation of ketones
Wang, Weifan,Luo, Man,Li, Jia,Pullarkat, Sumod A.,Ma, Mengtao
supporting information, p. 3042 - 3044 (2018/03/28)
The magnesium(i) complex [(XylNacnac)Mg]2 was employed as a highly efficient catalyst for the cyanosilylation of a variety of ketones with trimethylsilyl cyanide under mild conditions. In contrast to the traditional stoichiometric us
Preparation method of cyanalcohol silyl ether compound
-
Paragraph 0053; 0054; 0055, (2019/01/06)
The invention discloses a preparation method of a cyanalcohol silyl ether compound. The preparation method comprises usage of a catalyst, the catalyst is a tridentate forceps-shaped ligand-stabilizedmagnesium lithium bimetallic compound. According to the
Efficient and selective aldehyde cyanosilylation catalyzed by Mg-Li bimetallic complex
Li, Jia,Yu, Ting,Luo, Man,Xiao, Qian,Yao, Weiwei,Xu, Li,Ma, Mengtao
, p. 83 - 86 (2018/09/06)
A NCN-pincer ligand-based Mg-Li bimetallic complex [NCN-MgBr2][Li(THF)4] 1 has been employed as an efficient catalyst for cyanosilylation of a wide range of aldehydes with trimethylsilyl cyanide (TMSCN) at room temperature in CDClsu
Synthesis of [LAl(μ-S)2AlL] (L?=?HC(CMeNAr)2, Ar?=?2,6-Et2C6H3) with the insertion of sulfur into the Al–H bonds of LAlH2 and its application in catalysis
Zhong, Mingdong,Liu, Ying,Liu, Xin,Ma, Xiaoli,Yang, Zhi
supporting information, p. 182 - 185 (2017/05/24)
Two aluminum complexes [LAl(μ-S)2AlL] (1) and [LAl(SeH)2] (2) were synthesized in good yield by reacting one equivalent of LAlH2 (L?=?HC(CMeNAr)2, Ar?=?2,6-Et2C6H3) with one equivalent of S and with two equivalents of Se without any catalysts, respectively. Complexes 1 and 2 have been characterized by 1H and 13C NMR, elemental analyses, and single crystal X-ray structural analysis. Furthermore, the good catalytic activity of 1 as bimetallic Lewis acid catalyst for the addition reaction of TMSCN to aldehydes and aldimine condensation reactions, respectively, were investigated.
