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1,2,3,4-Tetra(methylene)cyclobutane, also known as cubane, is a highly strained organic compound with the molecular formula C8H8. It features a cube-like structure with four carbon atoms at each vertex and a methylene group (CH2) bridging each pair of adjacent carbon atoms. This unique geometry results in significant angle strain, as the ideal bond angle for sp3 hybridized carbon atoms is 109.5 degrees, while in cubane, the bond angles are only 90 degrees. Despite its instability, cubane has been synthesized and studied for its potential applications in materials science and as a model for understanding the effects of strain on molecular properties. Its synthesis involves a multi-step process, and its reactivity is influenced by the high degree of strain in its structure.

3227-91-6

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3227-91-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3227-91-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,2 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3227-91:
(6*3)+(5*2)+(4*2)+(3*7)+(2*9)+(1*1)=76
76 % 10 = 6
So 3227-91-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H8/c1-5-6(2)8(4)7(5)3/h1-4H2

3227-91-6Relevant academic research and scientific papers

Alicyclic Compounds, III. - New Method of Preparation and Reactions of Radialene

Trabert, Ludwig,Hopf, Henning

, p. 1786 - 1800 (2007/10/02)

Thermal isomerization of 1,8-bis(trimethylsiloxy)-2,6-octadiyne (9d) provides dimethylenecyclobutene 8d, which is transformed into the dichloride 8f by treatment of diol 8b with thionyl chloride.Reduction of 8f with zinc in ethylene glycol dibutyl ether c

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