32286-81-0

Usage

InChI:InChI=1/C13H14N2/c1-2-7-12(8-3-1)15-10-11-6-4-5-9-13(11)14-15/h1-3,7-8,10H,4-6,9H2

Upstream product

• 37719-81-6 2-phenyl-3,3a,4,5,6,7-hexahydro-2H-indazole 
• 100-63-0 phenylhydrazine 
• 1193-63-1 Cyclohexanone-2-carbaldehyde 
• 17649-90-0 2-(bis-methylsulfanyl-methylene)-cyclohexanone 
• 508191-77-3 3-phenylsydnone 
• 207505-17-7 2-(trimethylsilyl)cyclohexen-1-yl triflate 
• 3164-73-6 1-nitromethylcyclohexanol 
• 27861-39-8 (nitromethylene)cyclohexane 
• 108-94-1 cyclohexanone 
• 769092-24-2 2-[(dimethylamino)methyl]cyclohexanone 
• 610-14-0 2-nitrobenzyl chloride 
• 137-07-5 2-amino-benzenethiol 
• 6269-45-0 2-(2-nitrophenyl)benzo[d]thiazole 
• 29483-73-6 2-(2-aminophenyl)benzthiazole 

Downstream Products

• 3682-71-1 2-phenyl-2H-indazole 

Relevant academic research and scientific papers

1,3-Difunctionalization of β-alkyl nitroalkenes via combination of Lewis base catalysis and radical oxidation

Upon treatment with a Lewis base catalyst, β-alkyl-substituted nitroalkenes could be readily converted into allylic nitro compounds. Examples of either C-1 or C-3 functionalization methods have been reported through nitro-elimination, giving alkene products. In this work, successful 1,3-difunctionalization was achieved through a synergetic Lewis base catalysis and TBHP radical oxidation, giving vinylic alkoxyamines in good to excellent yields. This work further extended the general synthetic application of β-alkyl nitroalkenes.

Cycloadditions of cyclohexynes and cyclopentyne

We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described. The observed regioselectivities are explained by the distortion/interaction model.

Regioselective synthesis of 1-aryl-3,4-substituted/annulated-5-(methylthio) pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/annulated pyrazoles

Highly efficient and regioselective synthesis of 1-aryl-3,4-substituted/ annulated-5-(methylthio)-pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/ annulated pyrazoles has been reported via cyclocondensation of arylhydrazines with either α-oxoketene dithioacetals or β-oxodithioesters.

Competitive Cyclisations of Singlet and Triplet Nitrenes. Part 9. 2-(2-Nitrophenyl)-benzothiazoles and -benzimidazoles

2-(2-Nitrophenyl)benzothiazole, produced by deoxygenation of the corresponding nitro-compound or by thermolysis or photolysis of the related azide, gives indazolobenzothiazole by attack on the benzothiazole nitrogen.Similar attack of the nitrene in 2-(2-nitrophenyl)benzimidazoles gives benzimidazoindazoles in good yield.However, with an appropriate 1-substituent in the benzimidazole (e.g.Me or CHMe2) the nitrene in its triplet state (generated by acetophenone-sensitised photolysis or by thermolysis of the azide bearing a 4-dimethylamino-group) preferentially attacks this substituent giving benzimidazoquinazolines.