323-28-4

Upstream product

• 103-80-0 phenylacetyl chloride 
• 347-84-2 1-(4-fluorophenyl)-2-phenylethanone 
• 563-41-7 semicarbazide hydrochloride 
• 462-06-6 fluorobenzene 

Downstream Products

• 73424-52-9 4-(4-Fluorphenyl)-5-phenyl-1,2,3-thiadiazol 

Relevant academic research and scientific papers

Syntheses of 4,5-diaryl-1,2,3-thiadiazoles

Reaction of thionyl chloride with semicarbazones of 1-(4- methylsulfonylphenyl)-2-(4-substituted pheny)lethanone gave 4-(4- methylsulfonylphenyl)-5-(4-substituted) pheny-1,2,3-thiadiazoles 5. Compounds 5-phenyl-4-(substitutedphenyl)-1,2,3-thiadiazoles 14 were similarly prepared. Chlorosulfonation of the latter followed by ammonia gave the desired compounds 5-(4-aminosulfonylphenyl)-4-(substituted) phenyl-1,2,3-thiadiazoles 6. Copyright Taylor & Francis Inc.