323195-85-3

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 13720-58-6 1-(2,5-Dimethoxy-4-methyl-phenyl)-ethanone 

Downstream Products

• 678149-54-7 3-(2,5-dimethoxy-4-methylphenyl)but-2-enol 
• 878773-94-5 3,4,4-trimethyl-3-(2,5-dimethoxy-4-methylphenyl)cyclopentene 
• 878774-10-8 2-(2,5-dimethoxy-4-methyl-phenyl)-2,3,3-trimethyl-cyclopentanol 
• 878774-13-1 3-(2,5-dimethoxy-4-methyl-phenyl)-3,4,4-trimethyl-cyclopentanol 
• 878774-19-7 4-(2,5-dimethoxy-4-methylphenyl)-4,3,3-trimethylcyclopentanone 
• 678149-60-5 ethyl 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enoate 
• 864934-98-5 2-(2,5-dimethoxy-4-methyl-phenyl)-2-methyl-cyclopent-3-enecarboxylic acid ethyl ester 
• 864934-97-4 2-allyl-3-(2,5-dimethoxy-4-methyl-phenyl)-3-methyl-pent-4-enoic acid ethyl ester 
• 62185-66-4 (+/-)-lagopodin A 
• 678149-56-9 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enal 
• 678149-61-6 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enol 
• 678149-55-8 5-methyl-5-(2,5-dimethoxy-4-methylphenyl)hepta-1,6-dien-3-ol 
• 80952-78-9 (S)-(+)-Curcuhydroquinone 
• 69301-26-4 (S)-(-)-Curcuquinone 

Relevant academic research and scientific papers

Highly enantioselective iridium-catalyzed hydrogenation of α,β-unsaturated esters

α,β-Unsaturated esters have been employed as substrates in iridium-catalyzed asymmetric hydrogenation. Full conversions and good to excellent enantioselectivities (up to 99 % ee) were obtained for a broad range of substrates with both aromatic- and aliphatic substituents on the prochiral carbon. The hydrogenated products are highly useful as building blocks in the synthesis of a variety of natural products and pharmaceuticals. Asymmetric hydrogenation: A variety of α,β-unsaturated esters were hydrogenated with high enantioselectivities (see scheme). The hydrogenated products have been used in synthetic transformations as well as in formal total syntheses. Copyright

Total synthesis of enokipodins A-D and cuparene-1 ,4-diol

A Claisen rearrangement and RCM reaction based sequence has been developed for total synthesis of the antifungal sesquiterpenes enokipodins A-D and cuparene-1 ,4-diol starting from 2,5-dimethoxy-4-methythydroquinone. Copyright

The first total synthesis of (±)-lagopodin A

The first total synthesis of (±)-lagopodin A and a formal total synthesis of enokipodins A and B is described. The requisite precursors containing two vicinal quaternary carbon atoms were assembled employing Claisen rearrangement and an RCM reaction as ke

The First Total Synthesis of the Antimicrobial Sesquiterpenes (±)-Enokipodins A and B

Efficient first total synthesis of antimicrobial sesquiterpenes enokipodins A and B (1 and 2, respectively) and formal total synthesis of cuparene-1,4-diol (5) and cuparene-1,4-quinone (7) have been accomplished starting from 2,5-dimethoxy-4-methyl-acetop

Baker's yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol, (+)-xanthorrhizol, (-)-curcuquinone and (+)-curcuhydroquinone

Fermenting baker's yeast converts the unsaturated aldehydes 5a-c into the saturated alcohols 6a-c, respectively. The microbial saturation of substrates adsorbed on a nonpolar resin proceeds in high chemical yields and shows complete enantioselectivity in the formation of the (S)-(+) isomers. Enantiopure 6a-c are versatile chiral building blocks for the synthesis of bisabolane sesquiterpenes. Their usefulness is shown in the preparation of (S)-(+)-curcuphenol, (S)-(+)-xanthorrhizol, (S)-(-)-curcuquinone and (S)-(+)-curcuhydroquinone. The Royal Society of Chemistry 2000.