864934-97-4

Upstream product

• 678149-60-5 ethyl 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enoate 
• 106-95-6 allyl bromide 
• 323195-85-3 Ethyl (2E)-3-(2,5-dimethoxy-4-methylphenyl)but-2-enoate 
• 13720-58-6 1-(2,5-Dimethoxy-4-methyl-phenyl)-ethanone 
• 678149-54-7 3-(2,5-dimethoxy-4-methylphenyl)but-2-enol 

Downstream Products

• 864934-98-5 2-(2,5-dimethoxy-4-methyl-phenyl)-2-methyl-cyclopent-3-enecarboxylic acid ethyl ester 
• 62185-66-4 (+/-)-lagopodin A 
• 878774-19-7 4-(2,5-dimethoxy-4-methylphenyl)-4,3,3-trimethylcyclopentanone 
• 878774-13-1 3-(2,5-dimethoxy-4-methyl-phenyl)-3,4,4-trimethyl-cyclopentanol 
• 878774-10-8 2-(2,5-dimethoxy-4-methyl-phenyl)-2,3,3-trimethyl-cyclopentanol 
• 878773-94-5 3,4,4-trimethyl-3-(2,5-dimethoxy-4-methylphenyl)cyclopentene 
• 864934-94-1 4-acetoxy-5-methyl-2-(1,2,2-trimethylcyclopentyl)phenyl acetate 
• 864934-77-0 4-methoxy-5-methyl-2-(1,2,2-trimethylcyclopentyl)phenol 
• 243462-89-7 1-(2,5-dimethoxy-4-methylphenyl)-1,2,2-trimethyl-cyclopentane 
• 28917-12-6 (+/-)-cuparene-1,,4-quinone 
• 66389-30-8 5-methyl-2-(1,2,2-trimethylcyclopentyl)benzene-1,4-diol 

Relevant academic research and scientific papers

The first total synthesis of (±)-lagopodin A

The first total synthesis of (±)-lagopodin A and a formal total synthesis of enokipodins A and B is described. The requisite precursors containing two vicinal quaternary carbon atoms were assembled employing Claisen rearrangement and an RCM reaction as ke

Total synthesis of HM-1 and HM-2, aromatic sesquiterpenes isolated from the phytopathogenic fungus Helicobasidium mompa. Structure revision of HM-2

The structure assigned to the sesquiterpene HM-2 was found to be incorrect by total synthesis. A ring-closing metathesis based strategy was developed for the total synthesis of the aromatic sesquiterpene HM-1, which on functional group transformation established the structure of HM-2 as 23, a cuparene derivative.