80952-78-9

Upstream product

• 289507-53-5 (S)-1-(2,5-dimethoxy-4-methylphenyl)ethyl diisopropylcarbamate 
• 69301-26-4 (S)-(-)-Curcuquinone 
• 289507-52-4 1-((R)-2-Benzenesulfonyl-1,5-dimethyl-hex-4-enyl)-2,5-dimethoxy-4-methyl-benzene 
• 289507-51-3 (R)-1,4-dimethoxy-2-methyl-5-(1-(phenylsulfonyl)propan-2-yl)benzene 
• 289507-48-8 (S)-2-(2,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl acetate 
• 289507-50-2 1,4-Dimethoxy-2-methyl-5-((R)-1-methyl-2-phenylsulfanyl-ethyl)-benzene 
• 289507-47-7 2-(2,5-dimethoxy-4-methyl-phenyl)-propane-1,3-diol 
• 289507-49-9 (R)-2-(2,5-dimethoxy-4-methylphenyl)propan-1-ol 
• 323195-85-3 Ethyl (2E)-3-(2,5-dimethoxy-4-methylphenyl)but-2-enoate 
• 323195-88-6 (3S)-3-(2,5-Dimethoxy-4-methylphenyl)butyl iodide 
• 323195-93-3 (3S)-3-(2,5-Dimethoxy-4-methylphenyl)butan-2-ol 
• 678149-54-7 3-(2,5-dimethoxy-4-methylphenyl)but-2-enol 
• 323195-92-2 (2E)-3-(2,5-Dimethoxy-4-methylphenyl)but-2-enal 

Relevant academic research and scientific papers

A DITERPENE, A SESQUITERPENE QUINONE AND FLAVANONES FROM WYETHIA HELENIOIDES

The aerial parts of Wyethia helenioides afforded a new geranyl nerol derivative (a 16-hydroxy-18-oic acid), two isomeric prenylated flavanones and a quinone derived from bisabolene.The structures were elucidated by spectroscopic methods and some chemical

Total synthesis of s (+)-curcuphenol, s (+)-curcuquinone and s (+)-curcuhydroquinone

A synthesis of (-)-curcuphenol, (-)-curcuquinone and (-)-curcuhydroquinone from o-valerolactone is described. The key steps include an Evans asymmetric methylation of 5-(benzyloxy)pentanoic acid (5), an oxidative aromatization of enone (11) and a regioselective oxidation of the phenol to o-quinone derivative with bis(trifluoro acetate)iodobenzene.

Enantioselective total synthesis of heliannuols D and A

The enantioselective total synthesis of heliannuols D and A, which exhibits allelopathic activity, was discussed. The enantioselective total synthesis included base-mediated intramolecular cyclisation of phenolic epoxide. The analysis showed the preparation of configurationally defined enantiopure epoxide whose intramolecular aryl ether-forming reaction provided heliannuol D and/or heliannuol A.

Baker's yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol, (+)-xanthorrhizol, (-)-curcuquinone and (+)-curcuhydroquinone

Fermenting baker's yeast converts the unsaturated aldehydes 5a-c into the saturated alcohols 6a-c, respectively. The microbial saturation of substrates adsorbed on a nonpolar resin proceeds in high chemical yields and shows complete enantioselectivity in the formation of the (S)-(+) isomers. Enantiopure 6a-c are versatile chiral building blocks for the synthesis of bisabolane sesquiterpenes. Their usefulness is shown in the preparation of (S)-(+)-curcuphenol, (S)-(+)-xanthorrhizol, (S)-(-)-curcuquinone and (S)-(+)-curcuhydroquinone. The Royal Society of Chemistry 2000.