3233-36-1Relevant academic research and scientific papers
Active group closed diisocyanate for 3D object printing, composition and 3D object printing method and device
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Paragraph 0091-0094, (2021/08/07)
The invention provides active group closed diisocyanate for 3D object printing, a composition and a 3D object printing method and device. The invention provides active group closed diisocyanate for 3D object printing. The active group closed diisocyanate has a structure as shown in a formula 1; the active group closed diisocyanate can participate in a photopolymerization reaction under an optical radiation condition and can be used for printing a 3D object, in addition, the compound is beneficial to improving the mechanical property and the dimensional stability of the 3D object.
Kinetic studies of conjugate addition of amines to allenic and acrylic esters and their correlation with antibacterial activities against Staphylococcus aureus
Kiattisewee, Cholpisit,Kaidad, Angkit,Jiarpinitnun, Chutima,Luanphaisarnnont, Torsak
, p. 1059 - 1068 (2018/02/26)
Abstract: Kinetic reactivities of various allenic and acrylic esters in conjugate addition reactions with various amines were investigated. Competition experiments showed that amines reacted selectively with allenic esters, which was also confirmed by quantitative determination of the rate constants. The antibacterial activity against Staphylococcus aureus of allenic and acrylic ester derivatives were also determined. Allenic esters were found to exhibit a higher antibacterial activity than its acrylic counterparts. A correlation between the kinetic property and the antibacterial activity suggested that a conjugate addition may involve in the antibacterial mechanism of these unsaturated esters. Graphical abstract: [Figure not available: see fulltext.].
SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS
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Paragraph 00194, (2017/01/23)
Benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethyfase, including LSD1 and LSD2; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1 and/or LSD2.
Ring-closing metathesis dimerizations of enynes and deprotections of propargyl ethers mediated by carbene ruthenium complexes
Hahn, Dong-Woo,Byun, Dong-Min,Tae, Jinsung
, p. 63 - 67 (2007/10/03)
The ring-forming dimerizations of enynes were catalyzed by the first-generation carbene ruthenium complex, and the effects of the catalysts and ethylene gas were studied. The deprotection of propargyl ethers by the carbene ruthenium complexes is the first to be reported. Wiley-VCH Verlag GmbH & Co. KGaA1 69451 Weinheim, Germany, 2005.
Antimicrobial activity of p-hydroxyphenyl acrylate derivatives
Jung, Hee Kim,Park, Eun-Soo,Jae, Hun Shim,Kim, Mal-Nam,Moon, Woong-Sik,Chung, Kyoo-Hyun,Yoon, Jin-San
, p. 7480 - 7483 (2007/10/03)
To estimate the antimicrobial effect of p-hydroxyphenyl acrylate (H5) derivatives on the basis of their molecular structure, the hydroxy and acryl groups of p-hydroxyphenyl acrylate were modified. The antimicrobial activity of the resulting compounds was assessed against a Gram-positive bacterium (Staphylococcus aureus), a Gram-negative bacterium (Pseudomonas aeruginosa), and fungi (Aspergillus fumigatus and Penicillium pinphilum) by the halo zone and the shake flask test. The antimicrobial activity of H5 was ascribed mainly to the acryl group. Compounds with acryl or acryloxy groups bound to the phenyl moiety were found to exhibit particularly high antimicrobial activities. The activities of phenyl acrylate and phenyl vinyl ketone were excellent as compared to aliphatic acrylates such as cyclohexyl acrylate and hexyl acrylate, indicating that the stereoelectronic effect of the phenyl group was important to the antimicrobial activity.
