32353-38-1

Basic information

• Product Name: 3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline
• Synonyms: 3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline
• CAS NO: 32353-38-1
• Molecular Formula: C₁₉H₁₅N
• Molecular Weight: 257.3291
• Mol File: 32353-38-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 437.3°C at 760 mmHg
• Flash Point: 193°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 1.94E-07mmHg at 25°C
• Refractive Index: 1.726
• CAS DataBase Reference: 3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline(32353-38-1)
• EPA Substance Registry System: 3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline(32353-38-1)

Safety Data

• Hazardous Substances Data: 32353-38-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H15N/c1-2-6-14(7-3-1)12-16-10-11-17-13-15-8-4-5-9-18(15)20-19(16)17/h1-9,12-13H,10-11H2

Upstream product

• 5661-06-3 2,3-dihydro-1H-cyclopenta[b]quinoline 
• 100-52-7 benzaldehyde 
• 529-23-7 o-aminobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 109699-83-4 1,2-dihydro-cyclopenta[b]quinolin-3-one-(2,4-dinitro-phenylhydrazone) 
• 111639-66-8 1,2-dihydro-cyclopenta[b]quinolin-3-one-phenylhydrazone 
• 111411-97-3 3-(α-hydroxy-benzyl)-2,3-dihydro-1H-cyclopenta[b]quinolin-3-ol 

Relevant articles and documents

Direct alkenylation of alkylazaarenes with aldehydes through C(sp3)-H functionalization under catalytic InCl3 activation

Under the influence of InCl3 as a Lewis acid catalyst, a methodology on the C(sp3)-H functionalization of alkylazaarenes has been demonstrated through the activation of benzylic C-H bonds towards their addition reaction with the appropriate electrophiles. This methodology was chiefly applied in the direct alkenylation of primary and secondary benzylic C-H bonds of alkylazaarenes with aldehydes. A variety of alkenyl products were afforded in generally good yields including the starting alkenyl intermediate used in the synthesis of montelukast and other related molecules.