32380-83-9Relevant academic research and scientific papers
One-Pot Highly Regioselective Synthesis of Indole-Fused Pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones by a Smiles Rearrangement
Jiang, Xiaolei,Hu, Fangdong
supporting information, p. 1207 - 1210 (2018/03/23)
A simple and convenient synthesis of indole-fused pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones is described. A range of 2-(1 H -indol-2-yl)phenols and 4,5-dichloropyridazin-3-ones are compatible with this reaction. A Smiles rearrangement is proposed as a key step in the highly regioselective construction of the products. The easy availability of the starting materials makes this an appealing method in organic synthesis.
FeCl3 catalysed 7-membered ring formation in a single pot: A new route to indole-fused oxepines/azepines and their cytotoxic activity
Shiva, Kumar,Siddi Ramulu, Meesa,Rajesham, Bandari,Kumar, N. Praveen,Voora, Vani,Kancha, Rama Krishna
supporting information, p. 4468 - 4476 (2017/07/10)
Various oxepine and azepine fused N-heterocyclic derivatives were synthesized using a new and one-pot reaction of 2,3-dichloro quinoxaline/pyrazine with 2-(1H-indol-2-yl)phenol/aniline in the presence of 25 mol% FeCl3. The reaction proceeded vi
Remote anionic fries rearrangement of sulfonates: Regioselective synthesis of indole triflones
Xu, Xiu-Hua,Taniguchi, Misaki,Azuma, Ayaka,Liu, Guo Kai,Tokunaga, Etsuko,Shibata, Norio
supporting information, p. 686 - 689 (2013/03/29)
An unusual NaH-mediated remote anionic 1,5-thia-Fries rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.
