67338-35-6Relevant academic research and scientific papers
Remote anionic fries rearrangement of sulfonates: Regioselective synthesis of indole triflones
Xu, Xiu-Hua,Taniguchi, Misaki,Azuma, Ayaka,Liu, Guo Kai,Tokunaga, Etsuko,Shibata, Norio
supporting information, p. 686 - 689 (2013/03/29)
An unusual NaH-mediated remote anionic 1,5-thia-Fries rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.
Synthesis of some novel pyrazole derivatives of biological interest
Basawaraj, Raga,Gahininath, Wadikar,Chillargi, Neelavati,Alvi, Shah Nadeemuddin,Zaheeruddin
, p. 151 - 156 (2013/09/24)
The reaction of 5-chloro-2-hydroxyacetophenone 1 with hydrazine hydrate and phenyl hydrazine gave 4-chloro-2-(vhydrazinylideneethyl) phenol 2 and 4-chloro-2-1-(2-phenylhydrazinylidene) ethyl phenol 3 which on treatment with phosphorus oxychloride and DMF underwent cyclisation to furnish 3-(5-chloro-2-hydroxy phenyl)-1 H-pyrazole-4-carbaldehyde 4 and 3-(5-chloro-2-hydroxyphenyl)-1-phehyl-1 H-pyrazole-4-carbaldehyde 5 respectively. Further compounds 4 and 5 on treatment with substituted aromatic amines in presence of gl acetic acid in methanol gave title compounds 6-15.
HYDRAZONE DERIVATIVES AND THEIR USE AS BETA SECRETASE INHIBITORS
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Page/Page column 17; 24, (2008/06/13)
The invention relates to compounds having the general formula (I) wherein R3 is selected from the group consisting of H, methyl and hydroxyalkyl, and wherein Z1 and Z2are selected independently from one another from the gr
