324025-34-5

Upstream product

• 108-59-8 malonic acid dimethyl ester 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 22252-15-9 trans-4-methoxychalcone 
• 105-53-3 diethyl malonate 

Relevant academic research and scientific papers

Layered double hydroxides-supported diisopropylamide: Synthesis, characterization and application in organic reactions

The layered double hydroxides-supported diisopropylamide (LDH-DA) catalyst is found to be an efficient and selective solid base for aldol, Knoevenagel, Henry, Michael, transesterification and epoxidation reactions under liquid phase conditions. LDH-DA is synthesized by the interaction of lithium diisopropylamide with LDH-NO3 (as-synthesized) and calcined LDH-NO3. The LDH-DA (Mg/Al, 3/1) and their precursors are well characterized by using various instrumental techniques such as FT-IR, TGA and DTA, powder XRD, solid state 27Al MAS NMR spectroscopy, SEM and XPS (ESCA).

Lithium hydroxide catalyzed Michael addition - An easy handling and non-toxic protocol

Michael addition of dimethyl malonate to α,β-unsaturated ketones are reported in the presence of lithium hydroxide as an efficient catalyst of low toxicity, Moderate to high yield at room temperature is an added advantage of the reaction.

Chiral bisphosphazides as dual basic enantioselective catalysts

Chiral bisphosphazides complexed with lithium salts efficiently catalyze the direct enantioselective 1,4-addition of dialkyl malonates to acyclic enones. Spectroscopic studies on the stoichiometry of the bisphosphazide and lithium salt have indicated the

Magnesium-lanthanum mixed metal oxide: A strong solid base for the michael addition reaction

Michael additions were achieved quantitatively at room temperature with a broad spectrum of acceptors and donors, using a magnesium-lanthanum mixed oxide, a strong solid base. The best solvent for the reaction is dimethylformamide, but good yields were al

1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) catalyzed Michael reactions

1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD), a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. A wide variety of Michael donors and acceptors can participate in these reactions using 10-20 mol % of

Catalytic C-C bond formation promoted by Mg-Al-O-t-Bu hydrotalcite

Mg-Al-O-t-Bu-hydrotalcite catalyst was found to be an efficient, environmentally attractive and selective solid base catalyst for 1,4 Michael addition. Mg-Al-O-t-Bu hydrotalcite is also effective for simple synthesis of α,β-unsaturated esters and nitriles by condensation of the corresponding activated carboxylic esters or nitriles with various aldehydes by Knoevenagel condensation. These reactions proceeded at room temperature at a greater rate in the presence of Mg-Al-O-t-Bu hydrotalcite than in the presence of any of the other catalysts examined. (C) 2000 Elsevier Science Ltd.