324028-85-5

Basic information

• Product Name: 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI)
• Synonyms: 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI);5-Methoxy-6-nitropyridine-2-carboxylic acid;5-Methoxy-6-nitropicolinic acid;2-Pyridinecarboxylic acid, 5-Methoxy-6-nitro-
• CAS NO: 324028-85-5
• Molecular Formula: C₇H₆N₂O₅
• Molecular Weight: 198.14
• Product Categories: AMINOACID
• Mol File: 324028-85-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 433.234°C at 760 mmHg
• Flash Point: 215.812°C
• Appearance: /
• Density: 1.512g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI)(324028-85-5)
• EPA Substance Registry System: 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI)(324028-85-5)

Safety Data

• Hazardous Substances Data: 324028-85-5(Hazardous Substances Data)

Usage

General Description

2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI) is a chemical compound with the molecular formula C8H7NO5. It is a derivative of pyridinecarboxylic acid, with a methoxy group at position 5 and a nitro group at position 6. 2-Pyridinecarboxylicacid,5-methoxy-6-nitro-(9CI) is commonly used in organic synthesis and pharmaceutical research, as it can act as a building block for the synthesis of various biologically active compounds. It has also been studied for its potential pharmacological properties, including its potential as an antibacterial and antifungal agent. Additionally, the nitro group in this compound can be reduced to an amino group, which can further increase its versatility in chemical synthesis and drug development.

InChI:InChI=1/C7H6N2O5/c1-14-5-3-2-4(7(10)11)8-6(5)9(12)13/h2-3H,1H3,(H,10,11)

Upstream product

• 24015-98-3 3-methoxy-6-methyl-2-nitro-pyridine 
• 29082-92-6 5-methoxypyridine-2-carboxylic acid 

Downstream Products

• 390816-44-1 5-methoxy-6-nitro-pyridine-2-carboxylic acid methyl ester 

Relevant articles and documents

Oxalylchloride/DMF as an efficient reagent for nitration of aromatic compounds and nitro decarboxylation of cinnamic acids in presence of KNO 3 or NaNO2 under conventional and nonconventional conditions

Nitration of aromatic compounds and cinnamic acids with oxalylchloride/DMF afforded the corresponding nitro derivatives in the presence of KNO3 or NaNO2 under conventional and nonconventional (ultrasonic and microwave) conditions. The present methodology offers several benefits such as excellent yields, simple work-up procedure, and short reaction times. The yields obtained under present methodology are comparable with those obtained from (POCl3/DMF/KNO3 or NaNO2) and (SOCl 2/DMF/KNO3 or NaNO2) systems followed by shorter reaction times. The reaction times of sonication and microwave conditions are very shorter than those of the conventional conditions.

TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES

The present invention relates to a compound according to formula (I), wherein X and Y are either C and N or N and C; Z is CH2, CH2-CH2, CH2-NH, or NH; R1 is halogen, or R1 is alkyl, alkenyl

Viral polymerase inhibitors

An isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula I: wherein R1 is selected from: H, haloalkyl, (C1-6)alkyl, (C2-6)alkenyl, (C3-7)cycloalkyl, (C2-6)alkynyl, (C5-7)cycloalkenyl, 6 or 10-membered aryl, Het all optionally substituted; R2 is selected from (C1-6)alkyl, (C3-7)cycloalkyl, (C6-10)bicycloalkyl, 6- or 10-membered aryl, or Het all optionally substituted; B is N or CR5, wherein R5 is H, halogen, haloalkyl, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; X is N or CR5; D is N or CR5; each of Y1 and Y2 is independently O or S; Z is O, N, or NRz wherein Rz is H, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; R3 and R4 are each independently H, (C1-6)alkyl, first (C3-7)cycloalkyl or 6- or 10-membered aryl, Het (C1-6)alkyl-6- or 10-membered aryl, (C1-6)alkyl-Het; or each R3 and R4 are independently covalently bonded together to form second (C3-7)cycloalkyl, or heterocycle, all optionally substituted; or when Z is N, either R3 or R4 are independently covalently bonded thereto to form a nitrogen-containing heterocycle; R7 is H, (C1-6 alkyl), (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; or R7 is covalently bonded to either of R3 or R4 to form a heterocycle; A is (C1-6) alkyl-CONHR8 wherein R8 is-6- or 10-membered aryl, or Het; or A is a 6- or 10-membered aryl, or Het said aryl or Het being optionally substituted; or a salt or a derivative thereof; such compounds being potent inhibitors of HCV NS5B polymerase.