324530-37-2

Upstream product

• 97-30-3 Methyl-D-galactopyranoside 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 324530-38-3 ((2S,3R,4S,5R,6S)-3,4,5-Tris-benzyloxy-6-propa-1,2-dienyl-tetrahydro-pyran-2-yl)-methanol 
• 324530-47-4 (S)-2-((S)-3-Carboxy-2-{(R)-3-(4-heptyloxy-phenoxy)-2-[((2R,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-carbonyl)-amino]-propionylamino}-propionylamino)-pentanedioic acid dibenzyl ester 
• 324530-48-5 (S)-2-{[(1R,4R,7S,12S,13R,14R,15S)-13,14,15-Tris-benzyloxy-4-(4-heptyloxy-phenoxymethyl)-2,5,9-trioxo-10,16-dioxa-3,6-diaza-bicyclo[10.3.1]hexadecane-7-carbonyl]-amino}-pentanedioic acid dibenzyl ester 
• 324530-41-8 (S)-2-((S)-2-{(R)-3-Benzyloxy-2-[((2R,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-carbonyl)-amino]-propionylamino}-3-carboxy-propionylamino)-pentanedioic acid dibenzyl ester 
• 324530-42-9 (S)-2-[((1R,4R,7S,12S,13R,14R,15S)-13,14,15-Tris-benzyloxy-4-benzyloxymethyl-2,5,9-trioxo-10,16-dioxa-3,6-diaza-bicyclo[10.3.1]hexadecane-7-carbonyl)-amino]-pentanedioic acid dibenzyl ester 
• 324530-34-9 (2R,3S,4R,5R,6S)-3,4,5-Tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-carboxylic acid 

Relevant academic research and scientific papers

Design and synthesis of cyclic sialyl Lewis X mimetics: A remarkable enhancement of inhibition by pre-organizing all essential functional groups

Two rigid macrocyclic glycopeptides 1 and 2 were designed to mimic the tetrasaccharide SLe(X) as inhibitors of P-selectin. While compound 1 was found to be 1000-fold more potent than SLe(X) with IC50 = 1 μM, compound 2 was not soluble in water for evaluation of its activity. (C) 2000 Elsevier Science Ltd.

THE SYNTHESIS OF A CYCLOPROPYLGALACTOPYRANOSIDE

The synthesis of 2,3,4,6-tetra-O-acetyl-α-(2-ethoxycarbonylcyclopropyl)-D-galactopyranoside, 8, by copper-catalyzed thermolysis of ethyl diazoacetate in the presence of 2,3,4,6-tetra-O-acetyl-α-vinyl-D-galactopyranoside, 6, is reported.