32497-10-2

Basic information

• Product Name: 4-METHYL-1,3-THIAZOL-2(3H)-ONE
• Synonyms: 4-Methylthiazol-2(3H)-one;2(3H)-Thiazolone, 4-Methyl-;4-methyl-2(3H)-Thiazolone
• CAS NO: 32497-10-2
• Molecular Formula: C₄H₅NOS
• Molecular Weight: 115.15
• Mol File: 32497-10-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 259.5°C at 760 mmHg
• Flash Point: 110.8°C
• Appearance: /
• Density: 1.251g/cm³
• Vapor Pressure: 0.00797mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHYL-1,3-THIAZOL-2(3H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-1,3-THIAZOL-2(3H)-ONE(32497-10-2)
• EPA Substance Registry System: 4-METHYL-1,3-THIAZOL-2(3H)-ONE(32497-10-2)

Safety Data

• Hazardous Substances Data: 32497-10-2(Hazardous Substances Data)

Usage

General Description

4-METHYL-1,3-THIAZOL-2(3H)-ONE, also known as 4-methylthiazol-2-one, is a chemical compound with the molecular formula C4H5NOS. It is a heterocyclic organic compound that contains a thiazole ring with a methyl substituent at the 4-position. 4-METHYL-1,3-THIAZOL-2(3H)-ONE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has also been studied for its potential antimicrobial and antifungal properties. 4-METHYL-1,3-THIAZOL-2(3H)-ONE is a versatile building block in organic synthesis and has various industrial applications.

InChI:InChI=1/C4H5NOS/c1-3-2-7-4(6)5-3/h2H,1H3,(H,5,6)

Upstream product

• 3029-48-9 thiocyanoacetone 
• 683-63-6 O-methyl thiocarbamate 
• 78-95-5 chloroacetone 
• 625-57-0 O-ethyl thiocarbamate 
• 333-20-0 potassium thioacyanate 
• 475645-27-3 2-ethoxy-4-methyl-thiazole 
• 16687-42-6 ammonium thiocarbamate 
• 598-31-2 1-bromoacetone 

Downstream Products

• 533886-13-4 4-methyl-5-(4-nitro-phenylsulfanyl)-3H-thiazol-2-one 
• 533885-96-0 4-methyl-2-oxo-2,3-dihydro-thiazole-5-carbaldehyde 
• 100061-42-5 (4-methyl-thiazol-2-yl)-p-tolyl-amine 
• 4288-20-4 N,N'-bis-(4-methyl-thiazol-2-yl)-m-phenylenediamine 
• 32497-14-6 5-acetyl-4-methylthiazol-2(3H)-one 
• 90916-46-4 (4-methyl-thiazol-2-yl)-phenyl-amine 
• 693-95-8 4-Methylthiazole 
• 26847-01-8 2-chloro-4-methyl-1,3-thiazole 
• 115879-63-5 4-methyl-3-(2-pyridylmethyl)thiazol-2(3H)-one 

Relevant articles and documents

Synthesis of thiaazaheterocycle nucleoside analogues

The syntheses of thiazinone, thiazinedione and thiazolinone base modified nucleoside analogues have been discussed in both the deoxy- and ribosyl series. Both inter- and intramolecular N-glycosylations were evaluated.

Flavouring a foodstuff with compounds containing a sulphur atom linked to two specific atoms or groups

The invention relates to a process for flavouring foodstuffs by incorporating therein an effective amount of at least one compound R1-S-R2 with a specific, well defined structure such as (E)-2-methyl-1-(methylthio)-2-butene; S-ethyl thioformate; S-ethyl-2-(acetylamino)thioacetate; N-(2-methylthioethyl)acetamide; methyl-2-mercaptopropionate; propyl-2-mercaptopropionate; 2-(isopropylthio)pentane; 2-propenylthiol; 4-methyl-2-3H-thiazolone or tautomer; and 2,3-dimethyl-4-formylthiophene. The invention also covers a foodstuff and/or a flavouring concentrate containing at least one of the above identified compounds.

Studies on acetylenic compounds. XXVI. Ring closure. (6). New synthetic method of heterocyclic compounds from alpha-substituted acetylenic compounds.

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