325153-40-0Relevant academic research and scientific papers
A simple synthesis of aplysinopsin analogues by dimethylamine substitution in N,N-(dimethylamino)methylidene derivatives of five-membered heterocycles
Jak?e, Renata,Re?nik, Simon,Svete, Jurij,Golobi?, Amalija,Goli?, Ljubo,Stanovnik, Branko
, p. 8395 - 8403 (2001)
Some new aplysinopsin analogues were prepared by a simple coupling of N,N-(dimethylamino)methylidene substituted hydantoin, thiohydantoin, and thiazolone derivatives, with indole derivatives. Configuration around the exocyclic C=C double bond was determined on the basis of long-range heteronuclear coupling constants using 2D HMBC correlation technique.
