32550-59-7

Upstream product

• 115-18-4 2-methyl-3-buten-2-ol 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 78-79-5 isoprene 

Downstream Products

• 135940-08-8 5-Methoxy-8,8-dimethyl-2-phenyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 76288-48-7 5-Methoxy-2-(4-methoxy-phenyl)-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 119328-86-8 2-(3,4-Dimethoxy-phenyl)-5-methoxy-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 92413-38-2 1-(3,4-Dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-<(tetrahydro-2H-pyran-2-yl)oxyphenyl>-2-propen-1-on 
• 55395-04-5 3-Hydroxy-2-(4'-methoxyphenyl)-5-methoxy-8,8-dimethyl-9,10-dihydro-4H,8H-benzo<1,2-b:3,4-b'>dipyran-4-one 
• 88055-43-0 3-Hydroxy-2-(3',4'-dimethoxyphenyl)-5-methoxy-8,8-dimethyl-9,10-dihydro-4H,8H-benzo<1,2-b:3,4-b'>dipyran-4-one 
• 143885-67-0 (E)-3-(3,4-Dimethoxy-phenyl)-1-(5-hydroxy-7-methoxy-2,2-dimethyl-chroman-6-yl)-propenone 
• 25983-76-0 isoevodionol 
• 143885-65-8 5-hydroxy-7-methoxy-6-(4'-methoxy)cinnamoyl-2,2-dimethyl chroman 
• 4670-29-5 5-Hydroxy-2,8,8-trimethyl-8H-pyrano<2,3-h>chromone 
• 35930-31-5 Alloptaeroxylin methyl ether 
• 92413-41-7 Acetic acid (2S,3R,4S)-3-acetoxy-5-methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-4-yl ester 
• 92413-41-7 Acetic acid (2R,3R,4S)-3-acetoxy-5-methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-4-yl ester 
• 92413-40-6 (2S,3S,4S)-5-Methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromene-3,4-diol 

Relevant academic research and scientific papers

NUCLEAR ISOPRENYLATION OF POLYHYDROXYACETHOPHENONES ACID CATALYSED CONDENSATION WITH ISOPRENE

A novel method of nuclear isoprenylation leading to the exclusive formation of 2,2-dimethylchromans has been achieved by the direct condensation of polyhydroxyacetophenones with isoprene in presence of phosphoric acid.Acetylchromans, thus obtained, are dehydrogenated with DDQ to given corresponding 2,2-dimethylchromenes.Using this method, synthesis of number of naturally occuring chromenes, viz. ripariochromene A (6), eupatoriochromene (10), encecalin (11), isoevodionol (16), evodionol (17) and methylevodionol (18) has been affected.

A CONVENIENT SYNTHESIS OF ACETYLCHROMANS

A convenient one-step synthesis of acetylsubstituted 2,2-dimethylchromans involving the condensation of polyhydroxyacetophenones with 2-methylbut-3-ene-2-ol in presence of orthophosphoric acid is described.