32551-27-2

Basic information

• Product Name: Isothiazole, 4,5-diphenyl-
• CAS NO: 32551-27-2
• Molecular Formula: C15H11NS
• Molecular Weight: 237.325
• Mol File: 32551-27-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Isothiazole, 4,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isothiazole, 4,5-diphenyl-(32551-27-2)
• EPA Substance Registry System: Isothiazole, 4,5-diphenyl-(32551-27-2)

Safety Data

• Hazardous Substances Data: 32551-27-2(Hazardous Substances Data)

Upstream product

• 98-83-9 isopropenylbenzene 
• 83662-09-3 methyl(2-phenylprop-1-en-1-yl)sulfane 
• 591-50-4 iodobenzene 
• 936-46-9 4-Phenyl-isothiazole 
• 88406-86-4 2-Azido-4,5-diphenyl-[1,3]dithiole 
• 35540-16-0 4,5-diphenyl-isothiazole-3-carboxylic acid 
• 100-42-5 styrene 
• 60027-35-2 4-phenyl-1,3,2-oxathiazolylium-5-olate 
• 19881-68-6 (Z)-β-chloro-α,β-diphenylacrolein 
• 67-64-1 acetone 
• 65564-05-8 3-[(benzyloxycarbonyl)amino]propanal 
• 14063-81-1 (EZ)-3-chloro-2,3-diphenylacrylaldehyde 
• 108-94-1 cyclohexanone 
• 103-26-4 methyl cinnamate 

Relevant articles and documents

Access to 4-substituted isothiazoles through three-component cascade annulation and their application in C-H activation

The use of potassium ethyl xanthate (EtOCS2k) as a sulfur atom donor enabled the transition-metal-free [3 + 1 + 1] cascade annulation of isopropene derivatives with NH4I in DMSO/H2O, affording various 4-substituted isothiazoles in moderate to good yields

THERMOLYSIS OF 1,3-DITHIOL-2-YL AZIDES AND THERMAL PROPERTIES OF THE RESULTING 1,4,2-DITHIAZINES

2-Substituted 1,3-dithiol-2-yl azides, on thermolysis in refluxing toluene, give 3-substituted 1,4,2-dithiazines wich thermally extrude sulfur atom of the 4-position selectively to yield 3-substituted isothiazoles, while 2-unsubstituted 1,3-dithiol-2-yl azides undergo both ring expansion yielding 1,4,2-dithiazines and peculiar thermal dissociation into 1,3-dithiol-2-ylidene carbenes and hydrogen azide.