32599-84-1Relevant academic research and scientific papers
Chiral Bis(oxazoline) Ligands as C2-Symmetric Chiral Auxiliaries for the Synthesis of Enantiomerically Pure Bis-Cyclometalated Rhodium(III) Complexes
Grell, Yvonne,Demirel, Nemrud,Harms, Klaus,Meggers, Eric
, p. 3852 - 3859 (2019/11/13)
The synthesis of enantiomerically pure bis-cyclometalated rhodium(III) complexes using chiral bis(oxazoline) ligands as C2-symmetric chiral auxiliaries is described. Bis(oxazolines) are versatile chiral ligands for asymmetric catalysis but have
Design, synthesis and structure-activity relationship studies of novel 4 (1-adamantyl) phenyl analogues as hif-1α inhibitors
Xia, Yan,Duan, Qiong,Zhao, Bao-Hua,Li, Dong-Feng,Hou, Rui-Bin
, p. 338 - 346 (2016/07/06)
Hypoxia inducible factor-1 (HIF-1) is a key mediator during cancer cells to adapt tumor hypoxic condition. In this study, a series of adamantane-based compounds were synthesized and evaluated as potential inhibitors of HIF-1α. Examination of their structu
Design, synthesis and structure-activity relationship studies of novel 4 (1-adamantyl) phenyl analogues as HIF-1α inhibitors
Xiaa, Yan,Duana, Qiong,Zhaoa, Bao-Hua,Lia, Dong-Feng,Houa, Rui-Bin
, p. 338 - 346 (2016/10/11)
Hypoxia inducible factor-1 (HIF-1) is a key mediator during cancer cells to adapt tumor hypoxic condition. In this study, a series of adamantane-based compounds were synthesized and evaluated as potential inhibitors of HIF-1α. Examination of their structu
Facile approach for the synthesis of 2,3,4,9-tetrahydro-1H-xanthen-1-ones and 8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones via trapping of o-quinone methides
Osyanin, Vitaly A.,Ivleva, Elena A.,Klimochkin, Yuri N.
experimental part, p. 1832 - 1847 (2012/04/23)
An efficient, simple synthesis of 2,3,4,9-tetrahydro-1H-xanthene-1-ones and 8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones is reported by one-pot condensation of 3-dimethylamino-2-cyclohexen-1-ones with hydroxybenzyl alcohols, phenol, and 2-naphthol Mannich bases or their quaternized derivatives. The mechanism of the reaction is believed to involve the formation of the o-quinone methide intermediate. Copyright Taylor & Francis Group, LLC.
