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1-Ethoxy-2-fluoro-4-nitrobenzene is an organic compound with the molecular formula C8H7FNO3. It is a derivative of benzene, featuring a fluorine atom at the 2nd position, a nitro group at the 4th position, and an ethoxy group at the 1st position. 1-ethoxy-2-fluoro-4-nitrobenzene is characterized by its yellowish color and has a molecular weight of 191.14 g/mol. It is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactive functional groups, it can undergo various chemical reactions, such as nucleophilic aromatic substitution, making it a valuable building block in organic synthesis. However, it is important to handle 1-ethoxy-2-fluoro-4-nitrobenzene with care, as it may pose health risks and environmental concerns due to its potential toxicity and reactivity.

326-81-8

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326-81-8 Usage

Nitrobenzene derivative

A compound derived from nitrobenzene indicates that the structure of the compound is based on a benzene ring with a nitro group (-NO2) attached.

Ethoxy group at the 1-position

An ethoxy (-O-C2H5) group is attached to the benzene ring at the first position (1) refers to the specific location of the ethoxy group on the benzene ring.

Fluoro group at the 2-position

A fluoro (-F) group is attached to the benzene ring at the second position (2) refers to the specific location of the fluoro group on the benzene ring.

Nitro group at the 4-position

A nitro (-NO2) group is attached to the benzene ring at the fourth position (4) refers to the specific location of the nitro group on the benzene ring.

Commonly used in organic synthesis and pharmaceutical research

The compound is frequently utilized in the synthesis of other organic compounds and in the development of pharmaceutical drugs indicates the compound's applications and relevance in these fields.

Pale yellow liquid

The physical appearance of the compound is a pale yellow liquid describes the color and state (liquid) of the compound.

Slightly soluble in water

The compound has a low solubility in water indicates the compound's limited ability to dissolve in water.

Highly soluble in organic solvents

The compound dissolves easily in organic solvents describes the compound's high solubility in certain solvents.

Highly reactive compound

The compound is prone to reacting with other substances indicates the compound's chemical reactivity.

Potential hazards

The compound may pose risks to human health or the environment highlights the need for caution when handling the compound.

Check Digit Verification of cas no

The CAS Registry Mumber 326-81-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 326-81:
(5*3)+(4*2)+(3*6)+(2*8)+(1*1)=58
58 % 10 = 8
So 326-81-8 is a valid CAS Registry Number.

326-81-8Relevant academic research and scientific papers

HETEROCYCLIC COMPOUND

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Paragraph 0296, (2017/11/18)

Provided is a compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and is useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like

Pyrazolo[3,4-c]pyridine derivative

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Paragraph 0378; 0379; 0380, (2016/10/08)

The invention relates to a pyrazolo[3,4-c]pyridine derivative. The invention relates to a compound represented by a formula (I), a tautomer thereof, an optical isomer thereof or a pharmaceutically acceptable salt thereof, wherein the formula (I) is shown in the description, and Z, X, RNc, RNd, RNe and RNf are defined according to the claim 1. The invention further relates to the pharmaceutical composition contain the compound. The invention further relates to use of the compound or the pharmaceutical composition in preparing a drug for preventing and/or treating a disease which inhibits positive influence of an Xa factor, particularly use in preparing the drug for preventing and/or treating the disease which inhibits positive influence of the Xa factor under the condition of low hemorrhage risk.

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