32600-73-0 Usage
Derivative of thioamide
2-(methylamino)benzenecarbothioamide is derived from thioamide, which is a class of organic compounds containing a CS-N bond.
Benzene ring with a methylamino substituent
The compound contains a benzene ring, which is a six-membered aromatic ring, and has a methylamino group (-NHCH3) as a substituent attached to it.
Utilized in medicinal chemistry
2-(methylamino)benzenecarbothioamide is used in the field of medicinal chemistry as a potential formamide amidohydrolase inhibitor.
Formamide amidohydrolase inhibitor
The compound has the ability to inhibit the activity of formamide amidohydrolase, an enzyme involved in various biological processes.
Applications in the treatment of various diseases
Due to its inhibitory effects on formamide amidohydrolase, 2-(methylamino)benzenecarbothioamide could have applications in the treatment of various diseases.
Antitubercular activity
2-(methylamino)benzenecarbothioamide is reported to have antitubercular activity, making it a potential treatment option for tuberculosis.
Potential treatment for tuberculosis
The compound is currently being studied for its effectiveness in treating tuberculosis, a bacterial infection that primarily affects the lungs.
White solid
2-(methylamino)benzenecarbothioamide is a white solid, which is a common physical state for many organic compounds.
Stable under normal conditions
The compound is stable under normal conditions, making it suitable for research and industrial applications. This stability ensures that it can be handled and stored without undergoing unwanted chemical reactions or decomposition.
Check Digit Verification of cas no
The CAS Registry Mumber 32600-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,6,0 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 32600-73:
(7*3)+(6*2)+(5*6)+(4*0)+(3*0)+(2*7)+(1*3)=80
80 % 10 = 0
So 32600-73-0 is a valid CAS Registry Number.
32600-73-0Relevant academic research and scientific papers
Synthesis of substituted 2-benzoylaminothiobenzamides and their ring closure to substituted 2-phenylquinazoline-4-thiones
Hanusek, Jiri,Hejtmankova, Ludmila,Kubicova, Lenka,Sedlak, Milos
, p. 323 - 337 (2007/10/03)
Acylation of 2-aminothiobenzamide or 2-methylaminothiobenzamide with substituted benzoyl chlorides has been used to synthesise the corresponding 2-benzoyl-aminothiobenzamides whose subsequent sodium methoxide-catalysed ring closure gives the corresponding quinazoline-4-thiones. These compounds were characterised by means of their 1H- and 13C-NMR spectra. The preferred tautomeric form of selected compounds has been discussed on the basis of their 13C-NMR, IR and Raman spectra. It has been found that in the given medium 1-methyl-quinazoline-4-thiones undergo a replacement of the sulphur substituent by oxygen giving 1-methyl-quinazoline-4-ones. In strong acid media, 2-benzoylaminothiobenzamide is cyclised through its sulphur atom to give 2-phenylbenzo[d-1,3]thiazin-4-one.
