326476-71-5Relevant articles and documents
Enantioselective synthesis of (S)-N,N-diethyl-2-formyl-2-(methoxymethoxy)butyramide, a key intermediate for 20(S)-camptothecin analogues, via asymmetric bromolactonization
Jew, Sang-Sup,Roh, Eun-Young,Kim, Hee-Jin,Goo Kim, Myoung,Park, Hyeung-Geun
, p. 3985 - 3994 (2007/10/03)
A new enantioselective synthetic method for enantiomerically pure (S)-N,N-diethyl-2-formyl-2-(methoxymethoxy)butyramide 5, a versatile key intermediate has been developed employing asymmetric bromolactonization using (S)-proline as the chiral auxiliary. C