326476-83-9

Upstream product

• 109-89-7 diethylamine 
• 326476-81-7 (S)-2-benzyloxymethyl-2-(methoxymethoxy)butanoic acid 
• 4390-96-9 2-ethylacryloyl chloride 
• 1369495-20-4 (S)-2-ethyloxiran-2-carboxylic acid ethyl ester 
• 1369495-17-9 (R)-ethyl 2-bromomethyl-2-hydroxybutanoate 
• 1250440-84-6 (R)-2-bromomethyl-2-hydroxybutanoic acid 
• 1369495-16-8 (3R,8aR)-3-(bromomethyl)-3-ethyltetrahydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,4(3H)-dione 
• 1369495-13-5 (R)-1-(2-methylenebutanoyl)pyrrolidine-2-carboxylic acid 
• 1369495-24-8 (S)-ethyl 2-[(benzyloxy)methyl]-2-(methoxymethoxy)butanoate 
• 1369495-22-6 (S)-ethyl 2-[(benzyloxy)methyl]-2-hydroxybutanoate 
• 104306-94-7 2-benzyloxymethyl-but-2-en-1-ol 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 326476-73-7 1-(2-benzyloxymethyl-but-2-enoyl)-pyrrolidine-2-carboxylic acid 
• 326476-71-5 1-(2-benzyloxymethyl-but-2-enoyl)-pyrrolidine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Effective asymmetric synthesis of the key chiral building blocks of 20(S)- and 20(R)-camptothecins

An effective diastereoselective synthesis of (S)- N,N-diethyl-2-formyl-2- (methoxymethoxy)butanamide and (S)-2-formyl-2-(methoxymethoxy)butanoic acid ethyl ester, which are two key chiral building blocks for the synthesis of 20(S)-camptothecins, has been

Enantioselective synthesis of (S)-N,N-diethyl-2-formyl-2-(methoxymethoxy)butyramide, a key intermediate for 20(S)-camptothecin analogues, via asymmetric bromolactonization

A new enantioselective synthetic method for enantiomerically pure (S)-N,N-diethyl-2-formyl-2-(methoxymethoxy)butyramide 5, a versatile key intermediate has been developed employing asymmetric bromolactonization using (S)-proline as the chiral auxiliary. C