326487-11-0Relevant academic research and scientific papers
Sugar-derived Ras inhibitors: Group epitope mapping by NMR spectroscopy and biological evaluation
Peri, Francesco,Airoldi, Cristina,Colombo, Sonia,Mari, Silvia,Jimenez-Barbero, Jesus,Martegani, Enzo,Nicotra, Francesco
, p. 3707 - 3720 (2007/10/03)
Novel inhibitors of Ras protein activation have been found, containing a bicyclic core derived from D-arabinose and benzyl and phenylhydroxylamine moieties. NMR studies (trNOE, saturation-transfer difference, STD) of the binding between these molecules an
Arabinose-derived bicyclic amino acids: Synthesis, conformational analysis and construction of an αvβ3-selective RGD peptide
Peri, Francesco,Bassetti, Roberta,Caneva, Enrico,De Gioia, Luca,La Ferla, Barbara,Presta, Marco,Tanghetti, Elena,Nicotra, Francesco
, p. 638 - 644 (2007/10/03)
The synthesis, NMR structure determination, and molecular modelling of the conformationally restricted diastereomeric sugar azido acids 1 and 2 are presented. The bicyclic structures of these compounds are obtained through a iodocyclization reaction on th
