3268-81-3Relevant academic research and scientific papers
Synthesis of Gonadoliberin, a Gonadotropin Releasing Hormone
Rzeszotarska, Barbara,Masiukiewicz, Elzbieta,Kmiecik-Chmura, Halina
, p. 791 - 798 (2007/10/02)
A simple laboratory synthesis of gonadoliberin was elaborated basing on classical solution methods and using minimal protection of the side-chain functions.In the final step a hexapeptide segment was condensed with the corresponding tetrapeptide and the obtained product was purified by a single step silica gel chromatography.The total efficiency of the whole synthesis was 15percent.
Le chloroformiate d'isopropenyle (IPCF) en chimie des peptides. I. Un bon reactif pour le couplage peptidique : synthese de dipeptides modeles
Jaouadi, M.,Selve, C.,Dormoy, J. R.,Castro, B.
, p. 409 - 412 (2007/10/02)
Isopropenyl chloroformate was used as an activating agent of N-protected amino-acids in the mixed anhydride method.This new reagent allows to run mixed anhydrides couplings at room temperature.
