326915-65-5

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 109-77-3 malononitrile 
• 456-48-4 3-Fluorobenzaldehyde 
• 2972-71-6 3-fluorobenzylidenemalononitrile 

Relevant academic research and scientific papers

Task-specific ionic liquid as the recyclable catalyst for the rapid and green synthesis of dihydropyrano[3,2-c]chromene derivatives

A task-specific ionic liquid, [H3N+-CH2-CH2-OH][CH3COO-], was successfully applied as an efficient and reusable catalyst for the one-pot domino to approach to dihydropyrano[3,2-c]chromene derivatives with atom economy in a condensation reaction of 4-hydro

Fe3O4?SiO2-Sultone: A novel and recyclable magnetic nanocatalyst for the efficient synthesis of 3,4 dihydropyrano[c]chromenes and 2-amino-4H-chromene derivatives

A green, simple and eco-friendly procedure for the preparation of 3,4-dihydropyrano[c]chromenes and 2-amino-4H-chromene derivatives is described using Fe3O4?SiO2-Sultone as a novel and efficient magnetic nanocatalyst. All

2-amino-4-(3-fluoromethylbenzene)-3-cyano-5-oxo-4H,5H-pyrone and application thereof

The invention relates to a 2-amino-4-(3-fluorbenzene)-3-cyano-5-oxo-4H,5H-pyrone compound and an application thereof. The structural formula of the related compound is as shown in a formula I. The related application is the application of the related comp

One-pot synthesis of biscoumarin and dihydropyrano [c]chromene derivatives in the presence of organocatalysts under solvent-free conditions

A simple and efficient synthesis of biscoumarin and dihydropyrano[c]chromene derivatives using catalytic amounts of imidazole or isoquinoline as organocatalyst under solvent-free conditions is reported. The present procedure offers advantages such as high

Design, synthesis, docking study and biological evaluation of some novel tetrahydrochromeno [3′,4′:5,6]pyrano[2,3-b]quinolin-6(7H)-one derivatives against acetyl- and butyrylcholinesterase

Novel hybrid derivatives of two known scaffolds; tetrahydroaminoquinoline and coumarin were synthesized and evaluated for both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities. By means of an efficient nanocatalyst, the reaction time for the syntheses of the target compounds was reduced. Subsequently, Ellman's modified method was used to evaluate the enzyme inhibitory activity of the synthesized structures. It was observed that most hybrid structures were moderate to potent inhibitors of AChE compared to Tacrine as the reference drug among which 7f with 4-fluorophenyl substituent was the most active compound (IC50 = 5 nM).

Simple green approach to the synthesis of 2-amino-5-oxo-4,5- dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives catalyzed by 3-hydroxypropanaminium acetate (HPAA) as a new ionic liquid

A new ionic liquid, 3-hydroxypropanaminium acetate (HPAA) [H 3N+-CH2-CH2-CH2-OH] [CH3COO-], was synthesized for the first time and used as an efficient and recoverable catalyst i

Domino Knoevenagel condensation, Michael addition, and cyclization using ionic liquid, 2-hydroxyethylammonium formate, as a recoverable catalyst

The Knoevenagel condensation reaction of aromatic aldehydes with malononitrile or dimedone was investigated. Also, the three-component and one-pot synthesis of 2-amino-5-oxo-4-aryl-4,5-dihydropyrano[3,2-cchromene-3- carbonitrile derivatives by condensing