32710-92-2

Upstream product

• 105-36-2 ethyl bromoacetate 
• 120-46-7 1,3-diphenylpropanedione 
• 623-48-3 ethyl iodoacetae 

Downstream Products

• 65-85-0 benzoic acid 
• 2051-95-8 succinylbenzene 
• 289486-40-4 ethyl 4-phenyl-3-(1-phenylvinyl)pent-4-enoate 
• 32710-91-1 1,3,5-triphenyl-4-pyrazolylacetic acid 
• 32976-38-8 [1-(4-chloro-phenyl)-3,5-diphenyl-1H-pyrazol-4-yl]-acetic acid 
• 289486-42-6 4-phenyl-3-(1-phenylvinyl)pent-4-enal 

Relevant academic research and scientific papers

Synthesis and photochemical characteristics of novel tribenzoporphyrazines possessing peripherally annulated tetrahydrodiazepine and diazepine rings

Novel tribenzoporphyrazines possessing peripherally annulated tetrahydrodiazepine and diazepine rings were synthesized and characterized, and the substituent effects on their absorption spectra in various solvents and on singlet oxygen generation were stu

Concurrent Induction of Two Chiral Centers from Symmetrical 3,4-Disubstituted and 3,3,4-Trisubstituted 4-Pentenals Using Rh-Catalyzed Asymmetric Cyclizations

Asymmetric cyclization of symmetrical 3,4-disubstituted and 3,3,4-trisubstituted 4-pentenals was studied using Rh-complexes with chiral ligands. The cyclization of symmetrical 4-pentenals 4a,b by a neutral Rh[(R)-BINAP]Cl afforded cis-3,4-disubstituted (4R)-cyclopentanones 9a,b of >95% ee in 25-31% yields; on the other hand, the cyclization of 4a-c by a cationic Rh[(R)-BINAP]ClO4 afforded trans-3,4-disubstituted (4S)-cyclopentanones 10a-c of >95% ee in 70-81% yields. All stereoisomers could be stereoselectively made by the selection of a neutral or cationic Rh-complex, and (R)- or (S)-BINAP ligand. The Rh-catalyzed cyclization could be applied to the construction of cyclopentanones 17 and 18 bearing a chiral quaternary carbon. The cyclization by the cationic Rh[(R)-BINAP]ClO4 afforded the optically active trans-3,3,4-trisubstituted cyclopentanones 18a-c of 92-95% ee in 75-83% yields. The catalytic cycle was also studied by using deuterium aldehyde, and the tentative mechanisms of the enantio- and diastereoselection were proposed.

Pyrazol-4-acetic acid compounds

Pyrazol-4-acetic acid compounds, such as substituted pyrazol-4-acetic acid, its esters, amides, nitriles and their pharamaceutically acceptable salts and method for the preparation of these compounds are disclosed. The novel compounds are useful analgesics, anti-inflammatory, and antipyretics.