32763-20-5Relevant academic research and scientific papers
REACTIONS OF 1-ARYL-2,2-DICHLORO-1-PROPANONES. II. REACTION OF 1-(4-R-PHENYL)-2,2-DICHLORO-1-PROPANONES WITH SOME NUCLEOPHILES
Bratchanskii, P. E.,Komissarova, G. G.,Esipov, G. V.
, p. 1961 - 1964 (2007/10/02)
The reactions of 1-(4-R-phenyl)-2,2-dichloro-1-propanones with alkali-metal alkoxides and certain amines (morpholine, piperidine) and also their conversion into α-diketones were studied.By IR and mass spectrometry it was shown that the methoxylation of these compounds with sodium methoxide leads to the formation of the products from direct substitution of the halogen atoms by methoxyl groups.The kinetics of methoxylation are described by a second-order equation, and a Hammett correlation with a positive reaction constant is observed in the rate constants.
