328087-53-2Relevant academic research and scientific papers
Metabolically stabilized benzothiazoles for imaging of amyloid plaques
Henriksen, Gjermund,Hauser, Andrea I.,Westwell, Andrew D.,Yousefi, Behrooz H.,Schwaiger, Markus,Drzezga, Alexander,Wester, Hans-Jürgen
, p. 1087 - 1089 (2007/10/03)
Six new N-11C-labeled aminophenylbenzothiazoles substituted with fluorine in different positions have been synthesized and evaluated as amyloid-β binding ligands. Our structure-property relationship studies show that the substitution pattern of
Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles
Hutchinson,Chua,Browne,Trapani,Bradshaw,Westwell,Stevens
, p. 1446 - 1455 (2007/10/03)
Synthetic routes to a series of mono- and difluorinated 2-(4-amino-3-substituted-phenyl)benzothiazoles have been devised. Whereas mixtures of regioisomeric 5- and 7-fluorobenzothiazoles were formed from the established Jacobsen cyclization of precursor 3-
