32812-71-8Relevant academic research and scientific papers
Insertion of Alkylidene Carbenes into B-H Bonds
Yang, Ji-Min,Guo, Feng-Kai,Zhao, Yu-Tao,Zhang, Qiao,Huang, Ming-Yao,Li, Mao-Lin,Zhu, Shou-Fei,Zhou, Qi-Lin
, p. 20924 - 20929 (2020)
We have developed a protocol for insertion of alkylidene carbenes into the B-H bonds of amine-borane adducts, enabling, for the first time, the construction of C(sp2)-B bonds by means of carbene-insertion reactions. Various acyclic and cyclic alkenyl borane-amine adducts were prepared from readily accessible starting materials in good to high yields and were subsequently subjected to a diverse array of functional group transformations. The unprecedented spiro B-N heterocycles prepared in this study have potential utility as building blocks for the synthesis of pharmaceuticals. Preliminary mechanistic studies suggest that insertion of the alkylidene carbenes into the B-H bonds of the amine-borane adducts proceeds via a concerted process involving a three-membered-ring transition state.
A Search for Photoresolvable Mesogens: Synthesis and Properties of a Series of Liquid Crystalline, Axially Chiral 1-Benzylidene-4-phenyl>cyclohexanes
Zhang, Yifan,Schuster, Gary B.
, p. 1855 - 1862 (2007/10/02)
A series of axially chiral 1-benzylidene-4-ethynyl>phenyl>cyclohexanes was prepared in racemic form and as optically active mixtures by application of the Hanessian olefination reaction.These compounds have two spectrally overlapping g
