328123-65-5Relevant articles and documents
Chiral silver phosphate-catalyzed cycloisomeric kinetic resolution of α-allenic alcohols
Wang, Yan,Zheng, Kuan,Hong, Ran
, p. 4096 - 4099 (2012/04/10)
A kinetic resolution of α-allenic alcohols is realized through chiral silver phosphate-catalyzed cycloisomerization with high stereoselectivity (selectivity factor up to 189) and tolerance of a variety of functional groups. A mechanistic model is proposed to interpret the origin of the high stereoselectivity and broad substrate scope.