328546-89-0

Upstream product

• 124-40-3 dimethyl amine 
• 328543-07-3 4-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-benzaldehyde 
• 328543-05-1 1-(4-Diethoxymethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 328546-66-3 9-amino-1,2,3,4-tetrahydro-5H-benzo[e][1,4]diazepin-5-one 
• 5337-09-7 2-bromo-3-nitro-benzoic acid methyl ester 
• 328546-65-2 9-nitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one 

Downstream Products

• 328547-10-0 1-(4-Chloromethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 

Relevant academic research and scientific papers

Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors

Novel tricyclic benzimidazole carboxamide poly-(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been synthesized. Several compounds were found to be powerful chemopotentiators of temozolomide and topotecan in both A549 and LoVo cell lines. In vitro inhi

Tricyclic inhibitors of poly(ADP-ribose) polymerases

Compounds of the formula shown below are poly(ADP-ribosyl)transferase inhibitors: Such compounds are useful as therapeutics in treating cancers and in ameliorating the effects of stroke, head trauma, and neurodegenerative disease.