328548-20-5Relevant academic research and scientific papers
BENZOPYRONE ESTROGEN RECEPTOR REGULATOR
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, (2013/11/19)
The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.
BENZOPYRONE ESTROGEN RECEPTOR REGULATOR
-
, (2013/11/19)
The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.
B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance
Boumendjel, Ahcene,Bois, Frederic,Beney, Chantal,Mariotte, Anne-Marie,Conseil, Gwenaelle,Di Pietro, Attilio
, p. 75 - 77 (2007/10/03)
Starting from the interaction of galangin (3,5,7-trihydroxyflavone) with a cytosolic nucleotide-binding domain of P-glycoprotein, a series of flavonol derivatives was synthesized and tested for their binding affinity towards the same target. The 5,7-dihyd
