32871-88-8

Basic information

• Product Name: N-(3,4-dimethoxybenzyl)aminoacetaldehyde diethyl acetal
• Synonyms: N-(3,4-dimethoxybenzyl)aminoacetaldehyde diethyl acetal
• CAS NO: 32871-88-8
• Molecular Weight: 283.368
• Mol File: 32871-88-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-(3,4-dimethoxybenzyl)aminoacetaldehyde diethyl acetal(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-dimethoxybenzyl)aminoacetaldehyde diethyl acetal(32871-88-8)
• EPA Substance Registry System: N-(3,4-dimethoxybenzyl)aminoacetaldehyde diethyl acetal(32871-88-8)

Safety Data

• Hazardous Substances Data: 32871-88-8(Hazardous Substances Data)

Upstream product

• 5763-61-1 3,4-dimethoxybenzylamine 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 1604832-23-6 (E)-N-(3,4-dimethoxybenzylidene)-2,2-diethoxyethanamine 
• 6065-82-3 Ethyl diethoxyacetate 
• 61189-99-9 diethoxyacetamide 
• 645-36-3 2,2-diethoxy-ethanamine 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 58163-19-2 Veratryliden-aminoacetaldehyd-diethylacetal 

Downstream Products

• 78373-65-6 N-(3,4-dimethoxybenzyl)-N-methyl-2,2-diethoxyethylamine 
• 15248-39-2 6,7-dimethoxyisoquinoline 
• 3428-75-9 N-methyl-6,7-dimethoxyisoquinolinium iodide 
• 1604832-49-6 4-((6,7-dimethoxyisoquinolin-4-yl)methyl)-2-nitrophenol 
• 78373-77-0 benzylidene-3 dimethoxy-6,7 methyl-2 oxo-4 tetrahydroisoquinoleine 
• 131326-87-9 dimethoxy-6,7 hydroxy-4 (methoxy-4' phenyl)-4 methyl-2 tetrahydroisoquinoleine 
• 112663-98-6 isopapaverine N-oxide 
• 112663-97-5 6,7-dimethoxy-4-(3',4'-dimethoxybenzoyl)isoquinoline 
• 32871-93-5 6,7-dimethoxy-4-(3',4'-dimethoxybenzyl)isoquinoline 

Relevant articles and documents

Synthesis of new substituted 7,12-dihydro-6,12- methanodibenzo[c,f]azocine-5-carboxylic acids containing a tetracyclic tetrahydroisoquinoline core structure

A convenient and simple protocol has been developed for the synthesis of a series of new tetracyclic tetrahydroisoquinoline derivatives, 7,12-dihydro-6,12-methanodibenzo[c,f]-azocine-5-carboxylic acids by three component Petasis reaction with the use of aminoacetaldehyde acetals bearing substituted benzyl groups as the amine components followed by Pomeranz-Fritsch double cyclization reaction. By applying this method, several acids have been prepared in satisfactory yields. An unprecedented chemical behavior of a Petasis reaction product in diluted HCl solution leading to the formation of a phenylglycine derivative has been observed and the mechanism explaining such reactivity has been proposed.

SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE10A)

The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R', R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.

Etude de l'oxydation de tetrahydroisoquinoleinols-4 dimethoxyles en 6,7 ou 7,8, et sur la reactivite du carbonyle de la tetrahydroisoquinolone-4 dimethoxylee en 6,7

Preparation des tetrahydroisoquinoleinols-4 mentionnes ci-dessus, et etude de l'oxydation de ceux-ci au moyen de divers reactifs: oxydations chromiques, par les bromamides, le dimethylsulfoxide, la reaction d'Oppenauer.Seule cette derniere a conduit aux t