3289-38-1

Basic information

• Product Name: 4-Amino-6-chloro-2-diethylaminopyrimidine
• Synonyms: 4-Amino-6-chloro-2-diethylaminopyrimidine;6-chloro-N~2~,N~2~-diethyl-2,4-pyrimidinediamine(SALTDATA: FREE);6-chloro-N~2~,N~2~-diethyl-2,4-pyrimidinediamine
• CAS NO: 3289-38-1
• Molecular Formula: C8H13ClN4
• Molecular Weight: 200.67
• Mol File: 3289-38-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 355.1 °C at 760 mmHg
• Flash Point: 168.6 °C
• Appearance: /
• Density: 1.245 g/cm³
• Vapor Pressure: 3.19E-05mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: 4-Amino-6-chloro-2-diethylaminopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-6-chloro-2-diethylaminopyrimidine(3289-38-1)
• EPA Substance Registry System: 4-Amino-6-chloro-2-diethylaminopyrimidine(3289-38-1)

Safety Data

• Hazardous Substances Data: 3289-38-1(Hazardous Substances Data)

Usage

General Description

4-Amino-6-chloro-2-diethylaminopyrimidine is a chemical compound with the molecular formula C10H16ClN5. It is a pyrimidine derivative and is commonly used in the synthesis of pharmaceuticals and organic compounds. This chemical is known for its high reactivity and is used as an intermediate in the production of various drugs and agrochemicals. It is also used in research and development processes for the creation of new compounds with potential therapeutic applications. 4-Amino-6-chloro-2-diethylaminopyrimidine is an important building block in organic chemistry and plays a crucial role in the development of novel drugs and therapeutics.

InChI:InChI=1/C8H13ClN4/c1-3-13(4-2)8-11-6(9)5-7(10)12-8/h5H,3-4H2,1-2H3,(H2,10,11,12)

Upstream product

• 10132-07-7 4-amino-2,6-dichloropyrimidine 
• 109-89-7 diethylamine 
• 6299-25-8 4,6-Dichloro-2-(methylthio)pyrimidine 
• 100-46-9 benzylamine 
• 66380-47-0 4-amino-6-chloro-2-methylsulphinylpyrimidine 
• 74619-77-5 4-amino-6-chloro-2-methylsulphonylpyrimidine 

Relevant articles and documents

A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

Starting from commercially available 4-amino-2,6-dichloropyrimidine, a practical four steps synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines was developed. This strategy could introduce a diverse set of secondary amines and arylamines to displac

THE SYNTHESIS AND AMINOLYSIS OF SOME 4-CHLORO-2-(SUBSTITUTED)THIOPYRIMIDINES

Some 2-methylthio,2-methylsulphinyl and 2-methylsulphonyl-4-chloropyrimidines have been prepared.In each case which was studied except one the chloride ion was that which was preferentially displaced by diethylamine.The pseudo first order rate constant of for each reaction was determined the results showing that oxidation of the 2-methylthio group greatly enhances the rate of displacement of the 4-chloro group.