328955-86-8

Usage

Chemical Class

Benzoxazinones

Molecular Weight

217.26 g/mol

Derivative of

3,1-benzoxazin-2-one

Functional Groups

Amino group at position 6
Two methyl groups at position 4

Potential Applications

Pharmaceutical industry
Agricultural industry
Synthesis of other organic compounds

Biological Activities

Not specified, but potential for various biological activities

Utility

Building block in the development of new drugs
Building block in the development of agrochemicals

Upstream product

• 21440-96-0 1,4-Dihydro-4,4-dimethyl-1,3-benzo[d]oxazin-2-one 
• 551-93-9 2-aminoacetophenone 
• 15833-00-8 o-aminophenyldimethylcarbinol 
• 899438-52-9 6-(dibenzylamino)-4,4-dimethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one 
• 850198-52-6 4,4-dimethyl-6-nitro-1,4-dihydro-2H-3,1-benzoxazin-2-one 

Relevant academic research and scientific papers

SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-ones as progesterone receptor antagonists

We previously disclosed that 6-aryl benzoxazin-2-ones were PR modulators. In a continuation of this work we examined the SAR of new 6-arylamino benzoxazinones and found the targets 1-25, with an extra amino linker between the pendent 6-aryl groups and ben

AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR

The present invention provides a compound represented by the following formula (I): [wherein, A represents a group of the following formula (A-1): etc., R1 and R2 each independently represent a hydrogen atom etc., Z represents CR3 etc., W represents CR4 etc., Q represents CR5 etc., R3, R4 and R5 each independently represent a hydrogen atom etc., Y represents an oxygen atom or sulfur atom, X represents an oxygen atom etc. and B represents an optionally substituted aryl group or optionally substituted heteroaryl group], the prodrug thereof or the pharmaceutically acceptable salt thereof for preventing or treating various diseases such as hypertesion, cerebral stroke, cardiac failure, etc.