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1-(2-BOC-AMINO-PHENYL)-ETHANOL is a chemical compound characterized by its molecular formula C16H22N2O4. It is a white to off-white solid with a molecular weight of 302.35 g/mol. 1-(2-BOC-AMINO-PHENYL)-ETHANOL features a BOC-protected amino group and a hydroxyl group, which contribute to its versatility as an intermediate in organic synthesis. Its unique structure allows it to be a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. The BOC group's ease of removal under mild conditions further enhances its utility as a precursor for a diverse array of functionalized compounds, solidifying its role as a significant tool in organic chemistry.

328956-56-5

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328956-56-5 Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-BOC-AMINO-PHENYL)-ETHANOL is used as a key intermediate for the development of pharmaceuticals due to its ability to be incorporated into complex molecular structures. Its BOC-protected amino group ensures that the molecule can be selectively deprotected and functionalized, facilitating the synthesis of a wide range of therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 1-(2-BOC-AMINO-PHENYL)-ETHANOL is utilized as a versatile building block for the creation of various agrochemicals. Its chemical properties allow for the synthesis of compounds that can be used in pest control, crop protection, and other agricultural applications.
Used in Specialty Chemicals:
1-(2-BOC-AMINO-PHENYL)-ETHANOL is employed as a precursor in the synthesis of specialty chemicals, which are often used in niche applications such as high-performance materials, dyes, and other industrial chemicals. Its unique structure and functional groups make it suitable for the development of these specialized compounds.
Used in Organic Chemistry Research:
As a valuable tool in organic chemistry, 1-(2-BOC-AMINO-PHENYL)-ETHANOL is used in research settings to explore new synthetic pathways, develop novel reactions, and understand the reactivity of protected amino groups. Its ease of functionalization and deprotection makes it an ideal candidate for studying various organic transformations.

Check Digit Verification of cas no

The CAS Registry Mumber 328956-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,8,9,5 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 328956-56:
(8*3)+(7*2)+(6*8)+(5*9)+(4*5)+(3*6)+(2*5)+(1*6)=185
185 % 10 = 5
So 328956-56-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO3/c1-9(15)10-7-5-6-8-11(10)14-12(16)17-13(2,3)4/h5-9,15H,1-4H3,(H,14,16)

328956-56-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate

1.2 Other means of identification

Product number -
Other names GL-0164

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:328956-56-5 SDS

328956-56-5Relevant academic research and scientific papers

N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles

-

Paragraph 0065, (2015/11/27)

Transition metal-free catalytic methods for access to 2-arylindole compounds.

N-heterocyclic-carbene-catalyzed synthesis of 2-aryl indoles

Hovey, M. Todd,Check, Christopher T.,Sipher, Alexandra F.,Scheidt, Karl A.

supporting information, p. 9603 - 9607 (2014/10/15)

A convergent and efficient transition-metal-free catalytic synthesis of 2-aryl-indoles has been developed. The interception of a highly reactive and transient aza-ortho-quinone methide by an acyl anion equivalent generated through N-hetereocyclic carbene catalysis is central to this successful strategy. High yields and a wide scope as well as the streamlined synthesis of a kinase inhibitor are reported. Umpolung: N-heterocyclic carbene catalysis is used for the convergent and efficient transition-metal-free synthesis of 2-aryl-indoles. The interception of a highly reactive and transient aza-ortho-quinone methide by an acyl anion equivalent is central to this successful strategy. The reaction exhibits high yields and a wide scope, and it has been applied to a streamlined synthesis of a kinase inhibitor.

Enzymatic kinetic resolution of tert-butyl 2-(1-Hydroxyethyl) phenylcarbamate, a key intermediate to chiral organoselenanes and organotelluranes

Piovan, Leandro,Pasquini, Monica D.,Andrade, Leandro H.

experimental part, p. 8098 - 8109 (2011/11/06)

The enzymatic kinetic resolution of tert-butyl 2-(1-hydroxyethyl) phenylcarbamate via lipase-catalyzed transesterification reaction was studied. We investigated several reaction conditions and the carbamate was resolved by Candida antarctica lipase B (CAL

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