32896-90-5

Basic information

• Product Name: 5-NITRO-1-METHYL-2(1H)-PYRIDINONE
• Synonyms: 5-NITRO-1-METHYL-2(1H)-PYRIDINONE;1-Methyl-5-nitro-2(1H)-pyridinone;1-Methyl-5-nitro-1H-pyridin-2-one
• CAS NO: 32896-90-5
• Molecular Formula: C₆H₆N₂O₃
• Molecular Weight: 154.12
• Mol File: 32896-90-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 287.5 °C at 760 mmHg
• Flash Point: 127.7 °C
• Appearance: /
• Density: 1.37 g/cm³
• Vapor Pressure: 0.00248mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-NITRO-1-METHYL-2(1H)-PYRIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITRO-1-METHYL-2(1H)-PYRIDINONE(32896-90-5)
• EPA Substance Registry System: 5-NITRO-1-METHYL-2(1H)-PYRIDINONE(32896-90-5)

Safety Data

• Hazardous Substances Data: 32896-90-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 21, p. 874, 1978 DOI: 10.1021/jm00207a007Tetrahedron Letters, 12, p. 2211, 1971 DOI: 10.1016/S0040-4039(01)96822-4

InChI:InChI=1/C6H6N2O3/c1-7-4-5(8(10)11)2-3-6(7)9/h2-4H,1H3

Upstream product

• 694-85-9 1-methyl-2-pyridone 
• 73750-69-3 sodium methyl methanephosphonate 
• 5446-92-4 2-methoxy-5-nitropyridine 
• 100-39-0 benzyl bromide 
• 74-88-4 methyl iodide 

Downstream Products

• 4548-45-2 2-chloro-5-nitropyridine 
• 16098-21-8 3-bromo-1-methyl-5-nitropyridin-2(1H)-one 
• 14150-94-8 3,5-dinitro-1-methyl-2-pyridone 
• 33630-96-5 5-amino-1-methyl-1,2-dihydropyridin-2-one 
• 144677-14-5 2-(1H-pyrazol-3-yl)acetohydrazide 
• 1370652-56-4 {5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-aminopyridazin-3-yl}-N-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)carboxamide 
• 1370652-58-6 C₂₉H₃₂Cl₂FN₅O₇ 
• 90485-53-3 5‐amino‐1‐methylpiperidin‐2‐one 

Relevant articles and documents

Hilbert-Johnson reaction under high pressure: A facile preparation of 2-pyridones

For the first time, a facile synthesis of 2-pyridones utilizing a classical Hilbert-Johnson reaction of 2-methoxypyridines with haloalkanes under high pressure has been achieved. The reactions were sensitive to steric hindrance of haloalkanes.

NITRATION OF AROMATIC HETEROCYCLES WITH PALLADIUM(II) ACETATE AND SODIUM NITRITE.

Treatments of 1,3-dimethyluracil, 1-methyl-2-pyridone, and thiophene with palladium(II) acetate and sodium nitrite gave the corresponding nitro-substituted products.