32945-67-8

Basic information

• Product Name: L-Leucine, N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-L-leucyl]-, phenylmethyl ester
• CAS NO: 32945-67-8
• Molecular Formula: C30H49N3O6
• Molecular Weight: 547.736
• Mol File: 32945-67-8.mol

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-L-leucyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-L-leucyl]-, phenylmethyl ester(32945-67-8)
• EPA Substance Registry System: L-Leucine, N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl]-L-leucyl]-, phenylmethyl ester(32945-67-8)

Safety Data

• Hazardous Substances Data: 32945-67-8(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 71145-33-0 H-Leu₂-OBzl 
• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 
• 125814-33-7 N-(tert-butoxycarbonyl)-L-leucine N-carboxyanhydride 
• 73401-65-7 (S)-2-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoic acid 
• 1738-69-8 L-Leucine benzyl ester 
• 66450-17-7 Boc-Leu-HONB 
• 32925-57-8 Boc-Leu-Leu-OBzl 
• 87746-56-3 2-tert-butoxycarbonylamino-4-methyl-penatnoic acid benzyl ester 
• 100-39-0 benzyl bromide 

Downstream Products

• 75666-45-4 Boc-Ala₂-Leu₃-Pro₂-Leu₃-OBzl 
• 75666-43-2 H-Pro₂-Leu₃-OBzl*HCl 
• 75666-42-1 Boc-Pro₂-Leu₃-OBzl 
• 75666-41-0 Boc-Ala₂-Leu₃-OBzl 
• 92782-19-9 Boc-Leu₆-OBzl 
• 75666-40-9 H-Leu₃-OBzl 
• 95675-61-9 H-Leu₃-OBzl*HCl 

Relevant articles and documents

Peptide Mechanosynthesis by Direct Coupling of N-Protected α-Amino Acids with Amino Esters

In view of developing alternatives to classical peptide synthesis strategies that suffer from low efficacy and negative environmental impact, the reactivity of N-protected α-amino acids, amino esters, and N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide was

Environmentally benign peptide synthesis using liquid-assisted ball-milling: Application to the synthesis of Leu-enkephalin

This paper describes an original methodology for peptide bond synthesis avoiding toxic solvents and reactants. Ball-milling stoichiometric amounts of Boc-protected α-amino acid N-carboxyanhydrides (Boc-AA-NCA) or Boc-protected α-amino acid N-hydroxysuccin

A templating approach for monodisperse self-assembled organic nanostructures

The precise structural control is known for self-assembly into closed spherical structures (e.g., micelles), but similar control of open structures is much more challenging. Inspired by natural tobacco mosaic virus, we present the use of a rigid-rod template to control the size of a one-dimensional self-assembly. We believe that this strategy is novel for organic self-assembly and should provide a general approach to controlling size and dimension. Copyright

Application of a unique automated synthesis system for solution-phase peptide synthesis

An automated synthesis system, which is suitable for repetitive syntheses using similar reaction procedures, was used to synthesize systematically a library of all possible dipeptides (25) and tripeptides (125) from 5 protected amino acids. The apparatus has also been applied to the automated synthesis of 10 fragment tripeptide derivatives that are constituents of the hormone PACAP-27. The measured molecular optical rotation values of the library of 125 tripeptides were found to correlate well with calculated values obtained by summation of the molecular optical rotation values for the constituent amino acids.