329781-63-7

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 289712-62-5 2-Azidomethyl-N-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 289712-58-9 2-(azidomethyl)benzoyl chloride 
• 289712-57-8 2-(azidomethyl)benzoic acid 
• 329781-57-9 methyl 2-(azidomethyl) benzoate 
• 951-77-9 2'-Deoxycytidine 
• 51432-42-9 4-Amino-1-((2R,4S,5R)-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one 
• 2417-73-4 methyl 2-bromomethylbenzoate 

Downstream Products

• 76512-82-8 5'-O-(4,4'-dimethoxytrityl)deoxycytidine 

Relevant academic research and scientific papers

N-azidomethylbenzoyl blocking group in the phosphotriester synthesis of oligoribonucleotides

An effective modification of the phosphotriester method has been developed for the automatic synthesis of DNA and RNA fragments using O-nucleophilic intramolecular catalysis and the 2-(azidomethyl)benzoyl group for the protection of the amino groups of nucleotide heterocyclic bases.

2-(Azidomethyl)benzoyl as a new protecting group in nucleosides

A new protecting group, 2-(azidomethyl)benzoyl (AZMB), which can be easily removed by treatment with MePPh2 in dioxane-H2O or reduction with HCOONH4-Pd/C in dioxane-MeOH, was developed for protection of the hydroxy and amino functions of deoxyribonucleosides.