329977-73-3

Basic information

• Product Name: 3-(1-(3-chloropropyl)piperidin-4-yl)-6-fluorobenzo[d]isoxazole
• Synonyms: 3-(1-(3-chloropropyl)piperidin-4-yl)-6-fluorobenzo[d]isoxazole
• CAS NO: 329977-73-3
• Molecular Weight: 296.772
• Mol File: 329977-73-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(1-(3-chloropropyl)piperidin-4-yl)-6-fluorobenzo[d]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-(3-chloropropyl)piperidin-4-yl)-6-fluorobenzo[d]isoxazole(329977-73-3)
• EPA Substance Registry System: 3-(1-(3-chloropropyl)piperidin-4-yl)-6-fluorobenzo[d]isoxazole(329977-73-3)

Safety Data

• Hazardous Substances Data: 329977-73-3(Hazardous Substances Data)

Upstream product

• 150332-87-9 6-fluoro-3-[1-(3-hydroxypropyl)-4-piperidinyl]-1,2-benzisoxazole 
• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 84163-77-9 6-fluoro-3-(4-piperidinyl)benzo[d]isoxazole 
• 109-70-6 1.3-chlorobromopropane 
• 84163-13-3 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole hydrochloride 

Downstream Products

• 133454-47-4 iloperidone 

Relevant articles and documents

Discovery of a new class of multi-target heterocycle piperidine derivatives as potential antipsychotics with pro-cognitive effect

A series of benzoisoxazoleylpiperidine derivatives were synthesized by using the multi-target strategies and their potent affinities for dopamine (DA), serotonin (5-HT) and human histamine H3 receptors have been evaluated. Of these compounds, t

Development and Kilogram-Scale Synthesis of a D2/5-HT2A Receptor Dual Antagonist (±)-SIPI 6360

The kilogram-scale synthesis of a D2/5-HT2A receptor dual antagonist (±)-SIPI 6360 was developed as an alternative treatment for schizophrenia. Specifically, three conditions were modified and optimized, including the Vilsmeier condi

PROCESS FOR THE PREPARATION OF ILOPERIDONE

A process for the preparation of crystalline 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-ethanone (Iloperidone), which comprises the reaction between 3-[1-(3-chloropropyl)-4-piperidinyl]-6-fluoro-1,2-benzisoxazole and 3-methoxy-4-hydroxy-acetophenone.