32998-03-1

Basic information

• Product Name: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE
• Synonyms: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE
• CAS NO: 32998-03-1
• Molecular Formula: C₅H₅Cl₂N₃
• Molecular Weight: 178.02
• Mol File: 32998-03-1.mol

Chemical Properties

• Melting Point: 186 °C
• Boiling Point: 314.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.492±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.77±0.10(Predicted)
• CAS DataBase Reference: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(32998-03-1)
• EPA Substance Registry System: 2,6-DICHLORO-N-METHYL-4-PYRIMIDINAMINE(32998-03-1)

Safety Data

• Hazardous Substances Data: 32998-03-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dichloro-N-methyl-4-pyrimidinamine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,6-Dichloro-N-methyl-4-pyrimidinamine serves as an intermediate in the production of various agrochemicals. Its role in the synthesis of these compounds contributes to the development of effective solutions for agricultural challenges, such as pest control and crop protection.
Used in Organic Compounds Synthesis:
2,6-Dichloro-N-methyl-4-pyrimidinamine is utilized as a key intermediate in the synthesis of a wide range of organic compounds. Its versatility and reactivity in chemical reactions make it an essential component in the creation of diverse organic molecules for various applications.

Upstream product

• 3764-01-0 2,4,6-trichloropyrimidine 
• 64-17-5 ethanol 
• 74-89-5 methylamine 

Downstream Products

• 856974-71-5 (2,6-bis-benzyloxy-pyrimidin-4-yl)-methyl-amine 
• 856289-68-4 N²,N⁴-dimethyl-pyrimidine-2,4-diyldiamine 
• 34284-87-2 6-(methylamino)pyrimidine-2,4(1H,3H)-dione 
• 162265-98-7 2,6-dibenzyloxy-4-pyrimidine 
• 65766-32-7 6-chloro-N-methylpyrimidin-4-amine 

Relevant articles and documents

Substituted pyridine and pyrimidine derivatives and their use in treating viral infections

The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS

The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

NOVEL SEH INHIBITORS AND THEIR USE

The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme.

Pharmaceutically active bicyclic-heterocyclic amines

The pharmaceutically active bicyclic heterocyclic amines (XXX) STR1 where W1 is --N= or --CH=; W3 is --N= or --CH=; W5 is --N= or --CR5 -- with the proviso that W5 is --CR5 -- when both W1 and W3 are --N= which are useful as pharmaceuticals in treating mild and/or moderate to severe head injury, subarachnoid hemorrhage and subsequent ischemic stroke, asthma and reduction of mucous formation/secretion in the lung and other diseases and injuries.

Simplified analogues of acyclonucleosides. Synthesis of 6-[N-alkyl-N-(4- hydroxybutyl)amino]pyrimidine derivatives

The synthesis of some 6-alkylaminopyrimidine derivatives bearing a 4- hydroxybutyl chain as sugar mimic is described. These new compounds can be regarded as simplified, ring-opened analogues of purine acyclonucleosides.