33021-17-9

Basic information

• Product Name: 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL
• Synonyms: Inositol,1,2:5,6-di-O-cyclohexylidene-, D-myo- (8CI);Dispiro[cyclohexane-1,2'-benzo[1,2-d:3,4-d']bis[1,3]dioxole-7',1''-cyclohexane],D-myo-inositol deriv.
• CAS NO: 33021-17-9
• Molecular Formula: C₁₈H₂₈O₆
• Molecular Weight: 340.413
• Mol File: 33021-17-9.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL(33021-17-9)
• EPA Substance Registry System: 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL(33021-17-9)

Safety Data

• Hazardous Substances Data: 33021-17-9(Hazardous Substances Data)

Usage

Type

Derivative of inositol (a sugar alcohol)

Natural Sources

Found in various plant and animal sources

Usage

Pharmaceutical and medical research

Potential Treatments

a. Polycystic ovary syndrome (PCOS)
b. Gestational diabetes

Investigated Roles

a. Regulating insulin sensitivity
b. Glucose metabolism

Action

Believed to mimic the action of insulin

Functions

a. Promoting glucose uptake
b. Reducing insulin resistance in cells

Therapeutic Benefits

Being studied for managing conditions related to insulin resistance and glucose intolerance

Upstream product

• 101636-71-9 1,6-Di-O-acetyl-2,3:4,5-di-O-cyclohexylidene-D/L-myo-inositol 
• 1122-84-5 1-ethoxycyclohexene 
• 6763-47-9 rac-1,2-O-cyclohexylidene-myo-inositol 
• 933-40-4 cycloxexanone dimethyl ketal 
• 87-89-8 D-myo-inositol 
• 1670-47-9 1,1-diethoxycyclohexane 
• 6763-49-1 (+/-)-1,2:5,6-dicyclohexylidene-myo-inositol 
• 142034-40-0 C₂₀H₃₀O₇ 
• 125762-43-8 D-3-acetyl-1,2:5,6-di-O-cyclohexylidene-myo-inositol 
• 41545-19-1 (+)-1,2:5,6-di-O-cyclohexylidene-myo-inositol 
• 889659-13-6 1-O-butyryl-2,3:4,5-di-O-cyclohexylidene-myo-inositol 

Downstream Products

• 154097-44-6 C₂₉H₄₆O₈ 
• 158110-45-3 (-)-3,4-di-O-benzyl-1,2:5,6-di-O-cyclohexylidene-myo-inositol 
• 152697-27-3 (-)-3,4-di-O-benzyl-1,2-O-cyclohexylidene-myo-inositol 
• 154459-81-1 (-)-6-O-allyl-3,4,5-tri-O-benzyl-myo-inositol 
• 154372-19-7 C₃₆H₄₂O₆ 
• 154372-20-0 1D-6-O-allyl-3,4,5-tri-O-benzyl-1-O-(4-methoxybenzoyl)-myo-inositol 
• 211799-72-3 (-)-6-O-allyl-1-O-(p-methoxybenzyl)-2,3-O-cyclohexylidene-myo-inositol 
• 211869-78-2 6-O-allyl-1-O-(p-methoxybenzyl)-2,3:4,5-di-O-cyclohexylidene-myo-inositol 
• 151426-85-6 (-)-6-O-allyl-3,4-di-O-benzyl-1,2-O-cyclohexylidene-myo-inositol 
• 475650-91-0 (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol 
• 475650-90-9 C₃₇H₄₄O₇ 
• 475650-88-5 (-)-2-O-hexadecanoyl-1-O-(p-methoxybenzyl)-3,4,5-tri-O-benzyl-myo-inositol 
• 475650-92-1 (-)-6-O-allyl-2-O-hexadecanoyl-1-O-(p-methoxybenzyl)-3,4,5-tri-O-benzyl-myo-inositol 
• 475650-99-8 6-O-[2-azido-3,6-di-O-benzyl-2-deoxy-4-O-(2-propenyl)-α-D-glucopyranosyl]-2-O-hexadecanoyl-1-O-(p-methoxybenzyl)-3,4,5-tri-O-benzyl-myo-inositol 

Relevant articles and documents

Synthesis of substrate analogues as potential inhibitors for Mycobacterium tuberculosis enzyme MshC

Mycothiol cysteine ligase (MshC) is a key enzyme in the mycothiol (MSH) biosynthesis and a promising target for developing new anti-mycobacterial compounds. Herein, we report on the synthesis of substrate analogues, as potential inhibitors, for the MshC e

Synthesis of high-performance polyurethanes with rigid 5-6-5-fused ring system in the main chain from naturally occurring myo-inositol

A bisketal of myo-inositol was used as a diol-type monomer for synthesis of polyurethanes. The monomer was obtained by treatment of myo-inositol with 1,1-dimethoxycyclohexane in the presence of p-toluenesulfonic acid as a catalyst. The ketalization resulted in the formation of a 5-6-5-fused ring system, which endowed the diol-type monomer with high rigidity. The diol readily reacted with diisocyanate to give the corresponding polyurethane, which exhibited excellent heat resistance due to the rigid 5-6-5 system in the main chain. Copyright

Synthesis of a glycosylphosphatidylinositol anchor bearing unsaturated lipid chains

A GPI anchor bearing unsaturated fatty acid lipid chains (1) was synthesized by a highly convergent strategy employing the para-methoxybenzyl group for permanent hydroxyl protection. The final global deprotection was achieved by an efficient three-step, one-pot procedure to give an 81% isolated yield of the target structure.