154372-19-7Relevant academic research and scientific papers
First total synthesis of a GPI-anchored peptide
Xue, Jie,Shao, Ning,Guo, Zhongwu
, p. 4020 - 4029 (2007/10/03)
A GPI-anchored dipeptide of sperm CD52 antigen was prepared through a convergent synthesis. First, the dipeptide with its C-terminus free and the GPI with its nonreducing end phosphoeth-anolamine bearing a free amino group were synthesized separately. Then, the two building blocks were coupled with use of EDC/HOBt as the condensation reagent. Finally, the GPI-anchored peptide was deprotected to give the target molecule 1.
Convergent synthesis of an inner core GPI of sperm CD52
Xue, Jie,Guo, Zhongwu
, p. 2015 - 2018 (2007/10/03)
An inner core of the GPI anchor of sperm CD52 antigens was synthesized by a highly convergent process using specially modified inositol, glucosamine and phospholipid as key building blocks. This paper also presents a new and efficient procedure to prepare
Parasite Glucoconjugates. Part 1. The Synthesis of Some Early and Related Intermediates in the Biosynthetic Pathway of Glycosyl-phosphatidylinositol Membrane Anchors
Cottaz, Sylvain,Brimacombe, John S.,Ferguson, Michael A. J.
, p. 2945 - 2952 (2007/10/02)
The enantio-pure 1D- and 1L-myo-inositol derivative 3D and 3L have been used to prepare sodium 1D-6-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-myo-inositol sn-2,3-dipalmitoyloxypropyl phosphate 21 and a related 1,6-disubstituted 1L-myo-inositol 28, respective
