33037-74-0

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 20615-76-3 2-azidobenzyl alcohol 
• 16714-25-3 2-azidobenzaldehyde 
• 98-86-2 acetophenone 

Downstream Products

• 1022-86-2 2-benzoylindole 
• 612-96-4 2-Phenylquinoline 
• 127766-67-0 Acetic acid (4S,5R,6S)-6-(2-phenyl-[1,3]dithiolan-2-ylmethyl)-4-phenylsulfanyl-1-(2,2,2-trifluoro-acetyl)-1,2,3,4,5,6-hexahydro-benzo[b]azocin-5-yl ester 
• 133035-18-4 Acetic acid (4S,5R,6S)-4-benzenesulfinyl-6-(2-oxo-2-phenyl-ethyl)-1-(2,2,2-trifluoro-acetyl)-1,2,3,4,5,6-hexahydro-benzo[b]azocin-5-yl ester 
• 127766-68-1 Acetic acid (4S,5R,6S)-6-(2-oxo-2-phenyl-ethyl)-4-phenylsulfanyl-1-(2,2,2-trifluoro-acetyl)-1,2,3,4,5,6-hexahydro-benzo[b]azocin-5-yl ester 
• 127766-65-8 (4R,5S)-5-[(R)-1-(2-Amino-phenyl)-2-(2-phenyl-[1,3]dithiolan-2-yl)-ethyl]-4-phenylsulfanyl-dihydro-furan-2-one 
• 127766-69-2 Acetic acid (Z)-(5S,6S)-6-(2-oxo-2-phenyl-ethyl)-1-(2,2,2-trifluoro-acetyl)-1,2,5,6-tetrahydro-benzo[b]azocin-5-yl ester 
• 127766-66-9 (4S,5R,6S)-6-(2-Phenyl-[1,3]dithiolan-2-ylmethyl)-4-phenylsulfanyl-1,2,3,4,5,6-hexahydro-benzo[b]azocin-5-ol 
• 127766-73-8 Acetic acid (1aS,8R,9S,9aR)-9-hydroxy-8-(2-oxo-2-phenyl-ethyl)-1a,8,9,9a-tetrahydro-2H-1-oxa-3-aza-benzo[a]cyclopropa[e]cycloocten-3-yl ester 
• 127766-72-7 Acetic acid (Z)-(5S,6S)-5-hydroxy-6-(2-oxo-2-phenyl-ethyl)-5,6-dihydro-2H-benzo[b]azocin-1-yl ester 
• 127766-61-4 C₁₉H₁₇NO₄ 
• 127766-74-9 C₁₉H₁₅NO₃ 
• 127766-71-6 2-((Z)-(5S,6S)-1,5-Dihydroxy-1,2,5,6-tetrahydro-benzo[b]azocin-6-yl)-1-phenyl-ethanone 
• 127766-70-5 2-((Z)-(5S,6S)-5-Hydroxy-1,2,5,6-tetrahydro-benzo[b]azocin-6-yl)-1-phenyl-ethanone 

Relevant academic research and scientific papers

SYNTHETIC APPROACHES TOWARD FR-900482. I. STEREOSELECTIVE SYNTHESIS OF A PENTACYCLIC MODEL COMPOUND.

An efficient synthesis of a pentacyclic compound 18 possessing all the necessary handles to construct the unique skeleton of antitumor antibiotic FR-900482 1 is described.

Copper-Catalyzed Multicomponent Domino Reaction of 2-Bromobenzaldehydes, Aryl Methyl Ketones, and Sodium Azide: Access to 1 H-[1,2,3]Triazolo[4,5- c]quinoline Derivatives

A practical copper-catalyzed multicomponent reaction has been developed for the synthesis of 1H-[1,2,3]triazolo[4,5-c]quinoline derivatives from commercially available 2-bromobenzaldehydes, aryl methyl ketones, and sodium azide. This protocol integrated consecutive base-promoted condensation, [3 + 2] cycloaddition, copper-catalyzed SNAr, and denitrogenation cyclization sequences. Preliminary mechanistic studies revealed that CuBr2 acted as a multifunctional catalyst to streamline this domino process. The mild catalytic system enabled effective construction of one C-C and four C-N bonds in one operation.

Photochemical intramolecular cyclization routes to heterecycles

1-Aryl-3-(2-azidoaryl)prop-2-en-1-ones have been prepared from o-nitro aromatic aldehydes. The 2-aroylindole derivatives are easily prepared from these derivatives in a tandem reaction sequence in moderate yields. Photolytic process is found to be much mo