721965-60-2Relevant academic research and scientific papers
Potent and orally active ETA selective antagonists with 5,7-diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acid structures
Yoshizumi, Takashi,Takahashi, Hirobumi,Ohtake, Norikazu,Jona, Hideki,Sato, Yoshiyuki,Kishino, Hiroyuki,Sakamoto, Toshihiro,Ozaki, Satoshi,Takahashi, Hiroyuki,Shibata, Yoshihiro,Ishii, Yasuyuki,Saito, Michiyasu,Okada, Megumu,Hayama, Takashi,Nishikibe, Masaru
, p. 2139 - 2150 (2007/10/03)
The synthesis and structure-activity relationships of a series of 5,7-diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acids are described. Our efforts have been focused on modification of the aryl ring at the 5-position and the alkyl substituent at the 2-p
